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牛泛基因组联盟:为全球牛品种和其他牛种的基因组组装提供民主化的生产和获取途径。

The Bovine Pangenome Consortium: democratizing production and accessibility of genome assemblies for global cattle breeds and other bovine species.

机构信息

US Meat Animal Research Center, USDA-ARS, Clay Center, NE, 68933, USA.

Dairy Forage Research Center, USDA-ARS, Madison, WI, 53706, USA.

出版信息

Genome Biol. 2023 Jun 19;24(1):139. doi: 10.1186/s13059-023-02975-0.

DOI:10.1186/s13059-023-02975-0
PMID:37337218
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10278262/
Abstract

The Bovine Pangenome Consortium (BPC) is an international collaboration dedicated to the assembly of cattle genomes to develop a more complete representation of cattle genomic diversity. The goal of the BPC is to provide genome assemblies and a community-agreed pangenome representation to replace breed-specific reference assemblies for cattle genomics. The BPC invites partners sharing our vision to participate in the production of these assemblies and the development of a common, community-approved, pangenome reference as a public resource for the research community ( https://bovinepangenome.github.io/ ). This community-driven resource will provide the context for comparison between studies and the future foundation for cattle genomic selection.

摘要

牛泛基因组联盟(Bovine Pangenome Consortium,BPC)是一个致力于组装牛基因组以开发更完整的牛基因组多样性表示的国际合作组织。BPC 的目标是提供基因组组装和社区一致的泛基因组表示,以替代牛基因组学的特定品种参考组装。BPC 邀请具有我们共同愿景的合作伙伴参与这些组装的制作和共同的、社区认可的泛基因组参考的开发,作为研究社区的公共资源(https://bovinepangenome.github.io/)。这个由社区驱动的资源将为研究之间的比较提供背景,并为未来的牛基因组选择奠定基础。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4632/10278262/5a8d9be52ba6/13059_2023_2975_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4632/10278262/35aca3093e0e/13059_2023_2975_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4632/10278262/5a8d9be52ba6/13059_2023_2975_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4632/10278262/35aca3093e0e/13059_2023_2975_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4632/10278262/5a8d9be52ba6/13059_2023_2975_Fig2_HTML.jpg

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