Alhebshi Alhasan H, Aldekhail Mohammed, Abduljabbar Alaa
International Medical Center in Jeddah, Kingdom of Saudi Arabia.
Al-Qassim University Medical School, Qassim, Saudi Arabia.
J Surg Case Rep. 2023 Jun 16;2023(6):rjad291. doi: 10.1093/jscr/rjad291. eCollection 2023 Jun.
Extramammary Paget disease (EMPD) is an uncommon slow-growing skin adenocarcinoma originating in the anogenital region and axilla outside the mammary glands, often in regions with apocrine glands. The most common location is the vulva, followed by perineal, perianal, scrotal and penile skin. Here, we report a case of a 63-year-old male with EMPD in the perianal region. He reported 4 years of pain associated with an increasing region of skin irritation and bleeding on defecation that did not improve with topical agents. A biopsy sample revealed poorly differentiated carcinoma consistent with adenocarcinoma and associated with Paget disease. Workup was done. The patient tolerated local excision of the region well with no complications. A rare disease, EMPT, is challenging to diagnose and manage. Histopathological findings can, however, differentiate it from a wide array of similar skin conditions. Thorough investigations should be undertaken before initiating treatment to ensure the best outcomes.
乳房外佩吉特病（EMPD）是一种罕见的生长缓慢的皮肤腺癌，起源于乳腺外的肛门生殖器区域和腋窝，常见于有顶泌汗腺的区域。最常见的部位是外阴，其次是会阴、肛周、阴囊和阴茎皮肤。在此，我们报告一例63岁男性肛周EMPD病例。他自述4年来排便时疼痛，伴有皮肤刺激区域增大及出血，局部用药无改善。活检样本显示为低分化癌，符合腺癌且与佩吉特病相关。已进行了相关检查。患者对该区域的局部切除耐受良好，无并发症。EMPT是一种罕见疾病，诊断和治疗具有挑战性。然而，组织病理学检查结果可将其与多种类似的皮肤疾病相鉴别。在开始治疗前应进行全面检查以确保最佳治疗效果。
