通过Tc-99m-HMPAO标记白细胞SPECT/CT诊断为不明原因发热的假膜性结肠炎罕见病例。
Unusual Case of Pseudomembranous Colitis Presenting as Fever of Unknown Origin Diagnosed by Tc-99m-HMPAO-labeled Leukocytes SPECT/CT.
作者信息
Zambrano-Infantino Rosanna Del Carmen, Piñerúa-Gonsálvez Jean Félix, Alvarez-Mena Noelia, Izquierdo-Santervás Sandra, Alcaide Noelia, Garcia-Aragon Maria, Ruano-Pérez Ricardo
机构信息
Hospital Clínico Universitario de Valladolid, Department of Nuclear Medicine, Valladolid, Spain.
Hospital Clínico Universitario de Valladolid, Department of Gastroenterology, Valladolid, Spain.
出版信息
Mol Imaging Radionucl Ther. 2023 Jun 20;32(2):168-170. doi: 10.4274/mirt.galenos.2022.59354.
The fever of unknown origin (FUO) represents a complex diagnostic challenge due to the wide range of etiologies that could cause it, including neoplastic, infectious, rheumatic/inflammatory, and miscellaneous disorders. Several nuclear medicine techniques have proven to be valuable tools for guiding etiologic diagnosis in the setting of FUO. One of these is technetium-99m (Tc-99m)-hexamethylpropylene amine oxime (HMPAO)-labeled leukocyte scintigraphy, which is a diagnosis method that allows in most cases the localization and evaluation of the extension of an occult infection. This paper presents an uncommon case of pseudomembranous colitis without diarrhea as etiology of FUO diagnosed by Tc-99m-HMPAO-labeled leukocytes.
不明原因发热（FUO）是一项复杂的诊断挑战，因为可能导致该病症的病因范围广泛，包括肿瘤性、感染性、风湿性/炎症性及其他各类疾病。多种核医学技术已被证明是在不明原因发热情况下指导病因诊断的宝贵工具。其中之一是锝-99m（Tc-99m）-六甲基丙烯胺肟（HMPAO）标记的白细胞闪烁扫描，这是一种诊断方法，在大多数情况下能够对隐匿性感染的部位及扩展情况进行定位和评估。本文介绍了一例罕见的伪膜性结肠炎病例，该病例无腹泻症状，通过Tc-99m-HMPAO标记的白细胞被诊断为不明原因发热的病因。
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