Nyland H, Matre R, Tönder O
Acta Pathol Microbiol Scand C. 1979 Feb;87C(1):7-10.
Cryostat sections of human peripheral nerve tissue adsorbed sheep erythrocytes sensitized with antibody and human complement (EAC). Activated complement was essential for the reaction to occur. The receptor had specificity for the C3b fragment. In order to obrain binding to nerve tissue, the indicator cells had to be coated with more complement than that required for binding to C3b receptors in spleen and renal tissue. The receptors are located within the nerve fascicles and are probably of glycoprotein nature. The receptors for C3b in peripheral nerve tissus may be of significance in the deposition of immune complexes, which may play a role in acute polyradiculoneuritis.
人外周神经组织的冰冻切片吸附了用抗体和人补体致敏的绵羊红细胞（EAC）。活化的补体对于反应的发生至关重要。该受体对C3b片段具有特异性。为了实现与神经组织的结合，指示细胞必须比与脾脏和肾组织中的C3b受体结合所需的补体更多地包被补体。这些受体位于神经束内，可能具有糖蛋白性质。外周神经组织中C3b的受体可能在免疫复合物的沉积中具有重要意义，这可能在急性多发性神经根神经炎中起作用。
