Kurokawa Ichiro, Kobayashi Miwa, Nomura Yuko, Abe Masatoshi, Kerob Delphine, Dreno Brigitte
Department of Dermatology, Meiwa Hospital, Hyogo, Japan.
Kobayashi Dermatology Clinic, Fukuoka, Japan.
Dermatol Ther (Heidelb). 2023 Jul;13(7):1423-1433. doi: 10.1007/s13555-023-00943-x. Epub 2023 Jun 20.
In Japan, as in other countries around the world, acne vulgaris is a common disease and a frequent reason for patients to consult dermatologists. For optimal management of acne, it is important to understand how available products to support skin health can be used both with and without prescription products. Dermocosmetics can be defined as skincare agents with dermatologically active ingredients that directly support or care for the symptoms of various skin conditions (distinct from vehicle effects). There are products with active ingredients-including familiar ones such as niacinamide, retinol derivatives, and salicylic acid-that target important aspects of acne pathophysiology. Others, including ceramides, glyercin, thermal spring water, and panthenols, may have positive effects on skin barrier function that are useful in managing acne. This publication will discuss the roles of dermocosmetics in acne either as monotherapy to manage the milder forms of acne and help prevent relapses, or as adjuncts to prescription therapy to increase efficacy or adherence and assist in prevention of local adverse effects. Dermocosmetics may also have active ingredients that positively impact the skin microbiome.
在日本,与世界其他国家一样,寻常痤疮是一种常见疾病,也是患者咨询皮肤科医生的常见原因。为了实现痤疮的最佳管理,了解支持皮肤健康的现有产品如何与处方产品联合使用以及单独使用非常重要。皮肤化妆品可定义为含有具有皮肤病学活性成分的护肤品,这些成分可直接支持或护理各种皮肤状况的症状(不同于载体效应)。有一些产品含有活性成分,包括烟酰胺、视黄醇衍生物和水杨酸等常见成分,这些成分针对痤疮病理生理学的重要方面。其他成分,包括神经酰胺、甘油、温泉水和泛醇,可能对皮肤屏障功能有积极影响,有助于管理痤疮。本出版物将讨论皮肤化妆品在痤疮治疗中的作用,它既可以作为单一疗法来管理较轻形式的痤疮并帮助预防复发,也可以作为处方治疗的辅助手段来提高疗效或依从性,并有助于预防局部不良反应。皮肤化妆品还可能含有对皮肤微生物群有积极影响的活性成分。