Federal Research Center of Fundamental and Translational Medicine, Novosibirsk, Russia.
Bull Exp Biol Med. 2023 May;175(1):1-6. doi: 10.1007/s10517-023-05798-y. Epub 2023 Jun 20.
The study presents functional magnetic resonance imaging (fMRI) data on the brain activity in depression and psycho-diagnostic indicators that characterize cognitive activity strategies of positive social emotion regulation. It was shown that fMRI activity of the brain during viewing of emotionally neutral and moderately positive images and searching for an optimal self-regulation strategy was associated with changes in activation in the dorsomedial prefrontal cortex. Analysis of behavioral factors showed that strategies of searching for the optimal way of emotional self-regulation were closely related to the general style of behavior, level of uncertainty tolerance, and commitment. The integration of psycho-diagnostic and neuroimaging data allows deeper understanding of the mechanisms of emotions regulation that contributes to the optimization of protocols for the diagnosis and treatment of depressive disorders.
该研究提供了关于抑郁症大脑活动的功能磁共振成像（fMRI）数据，以及心理诊断指标，这些指标可以描述积极的社会情感调节的认知活动策略。研究表明，在观看情绪中性和适度积极的图像以及寻找最佳自我调节策略时，大脑的 fMRI 活动与背内侧前额叶皮层的激活变化有关。行为因素分析表明，寻找最佳情绪自我调节策略的策略与一般行为风格、不确定性容忍度和承诺密切相关。心理诊断和神经影像学数据的整合，有助于深入了解情绪调节机制，从而优化抑郁障碍的诊断和治疗方案。
