Department of General Surgery, Nanfang Hospital, The First School of Clinical Medicine, Southern Medical University, Guangzhou, Guangdong, People's Republic of China.
Guangdong Provincial Key Laboratory of Precision Medicine for Gastrointestinal Cancer, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong, People's Republic of China.
Dis Colon Rectum. 2023 Oct 1;66(10):1392-1401. doi: 10.1097/DCR.0000000000002653. Epub 2023 Jun 20.
Endoscopic radial incision and cutting procedure is a notable technique in the treatment of benign anastomotic strictures after low anterior resection in rectal cancer. However, the efficacy and safety of the endoscopic radial incision and cutting procedure and traditional endoscopic balloon dilation remain unknown.
To compare the efficacy and safety of the endoscopic radial incision and cutting procedure and endoscopic balloon dilation in patients with anastomotic stricture after low anterior resection.
Rectal cancer patients with anastomotic stricture after low anterior resection combined with synchronous preventive loop ileostomy between January 2014 and June 2021 were retrospectively collected. These patients underwent the endoscopic radial incision and cutting procedure or endoscopic balloon dilation as an initial treatment. The clinicopathological baseline data of the patients, endoscopic surgery success rate, complications, and restricture rate were analyzed.
This study was conducted at Nanfang Hospital in China.
A total of 30 patients were eligible after reviewing the medical records. Twenty patients underwent endoscopic balloon dilation, and 10 patients underwent endoscopic radial incision and cutting procedure.
The adverse event rate and stricture recurrence rate.
There were no significant differences in patient demographics or clinical features. No adverse events occurred in either of the 2 groups. The mean operation time was 18.9 ± 3.6 minutes in the endoscopic balloon dilation group and 10.2 ± 3.3 minutes in the endoscopic radial incision and cutting procedure group ( p < 0.001). The stricture recurrence rates between the endoscopic balloon dilation group and the endoscopic radial incision and cutting procedure group were significantly different (44.4% vs 0%; p = 0.025).
This was a retrospective study.
The endoscopic radial incision and cutting procedure is safe and more efficacious than endoscopic balloon dilation for anastomotic stricture after low anterior resection combined with synchronous preventive loop ileostomy in rectal cancer.
内镜下直肠前切除术后吻合口良性狭窄的放射状切开与切开术是一种重要的治疗方法。然而,内镜下放射状切开与切开术与传统内镜球囊扩张术的疗效和安全性尚不清楚。
比较内镜下放射状切开与切开术和内镜球囊扩张术治疗直肠前切除术后吻合口狭窄的疗效和安全性。
回顾性收集 2014 年 1 月至 2021 年 6 月间接受内镜下直肠前切除术后吻合口狭窄合并同期预防性回肠造口术的直肠癌患者。这些患者接受了内镜下放射状切开与切开术或内镜球囊扩张术作为初始治疗。分析患者的临床病理基线数据、内镜手术成功率、并发症和再狭窄率。
本研究在中国南方医院进行。
共 30 例患者符合入选标准,其中 20 例患者接受内镜球囊扩张术,10 例患者接受内镜下直肠前切除术后吻合口放射状切开与切开术。
不良事件发生率和狭窄复发率。
两组患者的人口统计学和临床特征无显著差异。两组均未发生不良事件。内镜球囊扩张组的平均手术时间为 18.9±3.6 分钟,内镜下直肠前切除术后吻合口放射状切开与切开术组的平均手术时间为 10.2±3.3 分钟(p<0.001)。内镜球囊扩张组和内镜下直肠前切除术后吻合口放射状切开与切开术组的狭窄复发率差异有统计学意义(44.4%比 0%;p=0.025)。
这是一项回顾性研究。
对于直肠前切除术后吻合口良性狭窄合并预防性回肠造口术的直肠癌患者,内镜下直肠前切除术后吻合口放射状切开与切开术安全且比内镜球囊扩张术更有效。