噪声引起的血流动力学和激素变化。

Hemodynamic and hormonal changes induced by noise.

作者信息

Andrén L, Hansson L, Björkman M, Jonsson A, Borg K O

出版信息

Acta Med Scand Suppl. 1979;625:13-8. doi: 10.1111/j.0954-6820.1979.tb00733.x.

DOI:10.1111/j.0954-6820.1979.tb00733.x

Abstract

Eighteen healthy male volunteers with normal hearing were exposed to industrial noise at different sound levels (75, 85 and 95 dB A) in a noise laboratory. Blood pressure, heart rate, stroke volume and cardiac output were recorded with noninvasive techniques. Adrenaline and noradrenaline concentration in venous plasma were analyzed before and during noise exposure. The mean resting blood pressure of the whole group was 120/70 mm Hg. During noise stimulation diastolic blood pressure increased (12.2%, p less than 0.001) as did mean arterial pressure (6.6%, p less than 0.001) and total peripheral resistance (12.7%, p less than 0.001). Stroke volume (7.3%, p less than 0.001) and cardiac output (5.0%, p less than 0.01) were both reduced at 95 dB A. Heart rate and systolic blood pressure did not change significantly. At 75 and 85 dB A there were similar but smaller changes in the hemodynamic parameters. There were no changes in adrenaline and noradrenaline in plasma during maximal noise exposure. The noise induced hemodynamic changes remained 5 minutes after the noise stimulation was stopped but had disappeared after 10 minutes of rest.

摘要

18名听力正常的健康男性志愿者在噪声实验室中暴露于不同声级（75、85和95分贝A）的工业噪声下。采用无创技术记录血压、心率、每搏输出量和心输出量。在噪声暴露前和暴露期间分析静脉血浆中的肾上腺素和去甲肾上腺素浓度。整个组的平均静息血压为120/70毫米汞柱。在噪声刺激期间，舒张压升高（12.2%，p<0.001），平均动脉压升高（6.6%，p<0.001），总外周阻力升高（12.7%，p<0.001）。在95分贝A时，每搏输出量（7.3%，p<0.001）和心输出量（5.0%，p<0.01）均降低。心率和收缩压无明显变化。在75和85分贝A时，血液动力学参数有类似但较小的变化。在最大噪声暴露期间，血浆中的肾上腺素和去甲肾上腺素没有变化。噪声刺激停止后5分钟，噪声引起的血液动力学变化仍然存在，但休息10分钟后消失。