Kalb R E, Grossman M E
J Am Acad Dermatol. 1986 Aug;15(2 Pt 2):353-6. doi: 10.1016/s0190-9622(86)70177-1.
Idiopathic hypoparathyroidism is a rare disorder produced by parathyroid hormone deficiency of unknown cause. It is often associated with other endocrine abnormalities. Patients with idiopathic hypoparathyroidism frequently develop ectodermal disease, including dry, rough skin: coarse, brittle hair; and lusterless, distally split nails. All of these complaints are relatively common in a dermatologic practice. Chronic mucocutaneous candidiasis is also a manifestation of idiopathic hypoparathyroidism. A patient is presented with a prominent ectodermal dysplasia and a chronic mucocutaneous candidiasis that were due to the underlying idiopathic hypoparathyroidism. A brief review of idiopathic hypoparathyroidism is included, as well as the implications of this diagnosis in terms of differential diagnosis, associated endocrine disorders, and therapy.
特发性甲状旁腺功能减退症是一种由不明原因的甲状旁腺激素缺乏引起的罕见疾病。它常与其他内分泌异常相关。特发性甲状旁腺功能减退症患者常出现外胚层疾病,包括皮肤干燥粗糙、头发粗糙易断、指甲无光泽且远端裂开。所有这些症状在皮肤科临床实践中都相对常见。慢性黏膜皮肤念珠菌病也是特发性甲状旁腺功能减退症的一种表现。本文介绍了一名因潜在的特发性甲状旁腺功能减退症而出现明显外胚层发育异常和慢性黏膜皮肤念珠菌病的患者。文中还简要回顾了特发性甲状旁腺功能减退症,以及该诊断在鉴别诊断、相关内分泌疾病和治疗方面的意义。