Pineles Beth L, Buskmiller Cara M, Qureshey Emma J, Stephens Angela J, Sibai Baha M
Department of Obstetrics, Gynecology, and Reproductive Sciences, McGovern Medical School at The University of Texas Health Science Center at Houston, Houston, TX (Drs Pineles, Buskmiller, Qureshey, Stephens, and Sibai).
Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, Perelman School of Medicine, University of Pennsylvania, Pennsylvania Hospital, Philadelphia, PA (Dr Pineles).
AJOG Glob Rep. 2023 May 28;3(3):100232. doi: 10.1016/j.xagr.2023.100232. eCollection 2023 Aug.
Cesarean delivery is a major source of maternal morbidity, and repeat cesarean delivery accounts for 40% of cesarean delivery, but recent data on the trial of labor after cesarean and vaginal birth after cesarean are limited.
This study aimed to report the national rates of trial of labor after cesarean and vaginal birth after cesarean by number of previous cesarean deliveries and examine the effect of demographic and clinical characteristics on these rates.
This was a population-based cohort study using the US natality data files. The study sample was restricted to 4,135,247 nonanomalous singleton, cephalic deliveries between 37 and 42 weeks of gestation, with a history of previous cesarean delivery and delivered in a hospital between 2010 and 2019. Deliveries were grouped by number of previous cesarean deliveries (1, 2, or ≥3). The trial of labor after cesarean (deliveries with labor among deliveries with previous cesarean delivery) and vaginal birth after cesarean (vaginal deliveries among trial of labor after cesarean) rates were computed for each year. The rates were further subgrouped by history of previous vaginal delivery. Year of delivery, number of previous cesarean deliveries, history of previous cesarean delivery, age, race and ethnicity, maternal education, obesity, diabetes mellitus, hypertension, inadequate prenatal care, Medicaid payer, and gestational age were examined concerning the trial of labor after cesarean and vaginal birth after cesarean using multiple logistic regression. SAS software (version 9.4) was used for all analyses.
The trial of labor after cesarean rates increased from 14.4% in 2010 to 19.6% in 2019 (<.001). This trend was seen in all categories of number of previous cesarean deliveries. Moreover, vaginal birth after cesarean rates increased from 68.5% in 2010 to 74.3% in 2019. The trial of labor after cesarean and vaginal birth after cesarean rates were the highest for deliveries with a history of both 1 previous cesarean delivery and a vaginal delivery (28.9% and 79.7%, respectively) and the lowest for those with a history of ≥3 previous cesarean deliveries and no history of vaginal delivery (4.5% and 46.9%, respectively). Factors associated with the trial of labor after cesarean and vaginal birth after cesarean rates are similar, but several factors have different directions of effect, such as non-White race and ethnicity, which is associated with a higher likelihood of trial of labor after cesarean but a lower likelihood of successful vaginal birth after cesarean.
More than 80% of patients with a history of previous cesarean delivery deliver by repeat scheduled cesarean delivery. With vaginal birth after cesarean rates increasing among those who attempt a trial of labor after cesarean, emphasis should be put on safely increasing the trial of labor after cesarean rates.
剖宫产是孕产妇发病的主要原因,再次剖宫产占剖宫产的40%,但近期关于剖宫产术后试产和剖宫产术后阴道分娩的数据有限。
本研究旨在按既往剖宫产次数报告全国剖宫产术后试产和剖宫产术后阴道分娩的发生率,并探讨人口统计学和临床特征对这些发生率的影响。
这是一项基于人群的队列研究,使用美国出生数据文件。研究样本仅限于4135247例妊娠37至42周、非异常单胎、头位分娩、有既往剖宫产史且于2010年至2019年在医院分娩的产妇。分娩按既往剖宫产次数(1次、2次或≥3次)分组。计算每年剖宫产术后试产(既往剖宫产分娩中伴有产程的分娩)和剖宫产术后阴道分娩(剖宫产术后试产中的阴道分娩)的发生率。这些发生率进一步按既往阴道分娩史进行亚组分析。使用多因素逻辑回归分析,研究分娩年份、既往剖宫产次数、既往剖宫产史、年龄、种族和族裔、产妇教育程度、肥胖、糖尿病、高血压、产前检查不足、医疗补助支付者和孕周与剖宫产术后试产和剖宫产术后阴道分娩的关系。所有分析均使用SAS软件(9.4版)。
剖宫产术后试产率从2010年的14.4%增至2019年的19.6%(P<.001)。在既往剖宫产次数的所有类别中均可见此趋势。此外,剖宫产术后阴道分娩率从2010年的68.5%增至2019年的74.3%。既往有1次剖宫产史且有阴道分娩史的产妇,其剖宫产术后试产率和剖宫产术后阴道分娩率最高(分别为28.9%和79.7%),而既往有≥3次剖宫产史且无阴道分娩史的产妇,其剖宫产术后试产率和剖宫产术后阴道分娩率最低(分别为4.5%和46.9%)。与剖宫产术后试产率和剖宫产术后阴道分娩率相关的因素相似,但有几个因素的影响方向不同,如非白人种族和族裔,其与剖宫产术后试产可能性较高相关,但与剖宫产术后成功阴道分娩可能性较低相关。
超过80%有既往剖宫产史的患者通过再次择期剖宫产分娩。随着剖宫产术后试产患者中剖宫产术后阴道分娩率的增加,应着重安全地提高剖宫产术后试产率。