Miyata Takashi, Nishiki Hisashi, Shinden Yuki, Motoyama Shota, Sannomiya Yuta, Tamezawa Hozumi, Nagayama Taigo, Hashimoto Akifumi, Kaida Daisuke, Miyashita Tomoharu, Fujita Hideto, Ueda Nobuhiko, Takamura Hiroyuki
Department of General and Digestive Surgery, Kanazawa Medical University Hospital, Kahoku, Japan.
J Surg Case Rep. 2023 Jun 19;2023(6):rjad349. doi: 10.1093/jscr/rjad349. eCollection 2023 Jun.
Anaplastic carcinoma of the pancreas (ACP) is an aggressive pancreatic tumor that grows rapidly, and its clinical characteristics are poorly defined because of its rarity. Thus, preoperative diagnosis is difficult and most definitive diagnoses are generally made by surgery, highlighting the importance of collecting more cases of ACP. We report a case of a 79-year-old woman with ACP that was difficult to diagnose preoperatively. Abdominal enhanced computed tomography revealed a large and expansive tumor in the spleen containing multilocular cystic and solid components. The first preoperative diagnosis was splenic angiosarcoma, and the tumor could be resected by distal pancreatectomy, total gastrectomy and partial transverse colectomy. ACP was first diagnosed based on postoperative histopathological findings. ACP that spreads to the spleen and forms an intrasplenic mass is rare. However, ACP should be included in the differential diagnosis of such patients, and further research of ACP is essential for a favorable prognosis.
胰腺未分化癌（ACP）是一种侵袭性胰腺肿瘤，生长迅速，因其罕见，其临床特征尚不明确。因此，术前诊断困难，大多数确诊通常通过手术进行，这凸显了收集更多ACP病例的重要性。我们报告一例79岁女性ACP患者，术前难以诊断。腹部增强计算机断层扫描显示脾脏有一个巨大的扩展性肿瘤，包含多房囊性和实性成分。术前初步诊断为脾血管肉瘤，该肿瘤可通过胰体尾切除术、全胃切除术和部分横结肠切除术切除。根据术后组织病理学结果首次诊断为ACP。扩散至脾脏并形成脾内肿块的ACP罕见。然而，此类患者的鉴别诊断应包括ACP，对ACP进行进一步研究对良好预后至关重要。
