Department of Animal Sciences, Federal Rural University of the Semi-Arid (UFERSA), Mossoró, RN, Brazil.
Graduated from the State University of Londrina (UEL), Londrina, PR, Brazil.
J Therm Biol. 2023 May;114:103561. doi: 10.1016/j.jtherbio.2023.103561. Epub 2023 Apr 7.
Medical thermography is an imaging test used to monitor skin surface temperature. Although it is not a recent technique, significant advances have been made since the 2000s with the equipment modernization, leading to its popularization. In cancer diagnosis, the application of thermography is supported by the difference in thermal distribution between neoplastic processes and adjacent healthy tissue. The mechanisms involved in heat production by cancer cells include neoangiogenesis, increased metabolic rate, vasodilation, and the release of nitric oxide and pro-inflammatory substances. Currently, thermography has been widely studied in humans as a screening tool for skin and breast cancer, with positive results. In veterinary medicine, the technique has shown promise and has been described for skin and soft tissue tumors in felines, mammary gland tumors, osteosarcoma, mast cell tumors, and perianal tumors in dogs. This review discusses the fundamentals of the technique, monitoring conditions, and the role of thermography as a complementary diagnostic tool for cancer in veterinary medicine, as well as future perspectives for improvement.
医学热成像技术是一种用于监测皮肤表面温度的成像测试方法。虽然它不是一种新技术,但自 21 世纪以来,随着设备的现代化,它取得了重大进展,因此得到了普及。在癌症诊断中,热成像的应用得到了支持,因为肿瘤过程和相邻健康组织之间的热分布存在差异。癌细胞产生热量的机制包括新血管生成、代谢率增加、血管扩张以及一氧化氮和促炎物质的释放。目前,热成像已在人类中广泛研究作为皮肤和乳腺癌的筛查工具,取得了积极的结果。在兽医领域,该技术显示出了前景,并已在猫科动物的皮肤和软组织肿瘤、乳腺肿瘤、骨肉瘤、肥大细胞瘤和犬的肛周肿瘤中得到描述。本文综述了该技术的基本原理、监测条件以及热成像作为兽医癌症辅助诊断工具的作用,以及未来的改进前景。