Andrew Caroline, Fleischer Christina M, Camblor Pablo Martinez, Chow Vinca, Briggs Alexandra, Deiner Stacie
Department of Anesthesia, Critical Care, and Pain Medicine, Massachusetts General Hospital, Boston, MA, USA.
Department of General Surgery, Michigan Medicine, University of Michigan, Ann Arbor, MI, USA.
Perioper Med (Lond). 2023 Jun 21;12(1):28. doi: 10.1186/s13741-023-00313-3.
Older adults comprise 40% of surgical inpatients and are at increased risk of postoperative rehospitalization. A decade ago, 30-day rehospitalizations for Medicare patients were reported as 15%, and more than 70% was attributed to medical causes. In the interim, there have been several large-scale efforts to establish best practice for older patients through surgical quality programs and national initiatives by Medicare and the National Health Service. To understand the current state of rehospitalization in the USA, we sought to report the incidence and cause of 30-day rehospitalization across surgical types by age.
We performed a retrospective study utilizing the American College of Surgeons National Surgical Quality Improvement Program (ACS NSQIP) dataset from 2015 to 2019. Our primary exposure of interest was age. Patients were categorized into four groups: 18-49, 50-64, 65-74, and 75 + years old. Reasons for rehospitalization were evaluated using NSQIP defined causes and reported International Classification of Disease (ICD)-9 and ICD-10 codes. Our primary outcome was the incidence of unplanned 30-day rehospitalization and secondary outcome the cause for rehospitalization. Variables were summarized by age group through relative (%) and absolute (n) frequencies; chi-square tests were used to compare proportions. Since rehospitalization is a time-to-event outcome in which death is a competing event, the cumulative incidence of rehospitalization at 30 days was estimated using the procedure proposed by Gray. The same strategy was used for estimating the cumulative incidence for unplanned rehospitalizations.
A total of 2,798,486 patients met inclusion criteria; 198,542 had unplanned rehospitalization (overall 7.09%). Rehospitalization by age category was 6.12, 6.99, 7.50, and 9.50% for ages 18-49, 50-64, 65-74, and 75 + , respectively. Complications related to the digestive system were the single most common cause of rehospitalization across age groups. Surgical site infection was the second most common cause, with the relative frequency decreasing with age as follows: 21.74%, 19.08%, 15.09%, and 9.44% (p < .0001). Medical causes such as circulatory or respiratory complications were more common with increasing age (2.10%, 4.43%, 6.27%, 8.86% and 3.27, 4.51, 6.07, 8.11%, respectively).
We observed a decrease in overall rehospitalization for older surgical patients compared to studies a decade ago. The oldest (≥ 75) surgical patients had the highest 30-day rehospitalization rates (9.50%). The single most common reason for rehospitalization was the same across age groups and likely attributed to surgery (ileus). However, the aggregate of medical causes of rehospitalization was more common in older patients; surgical and respiratory reasons were twice as common in this group. Rehospitalization increased by age for some surgery types, e.g., lower extremity bypass, more than others, e.g., ventral hernia repair. Future investigations should focus on interventions to reduce medical complications and further decrease postoperative rehospitalization for older surgical patients undergoing high-risk procedures.
老年患者占外科住院患者的40%,术后再次住院风险增加。十年前,医疗保险患者30天内的再住院率报告为15%,其中70%以上归因于医疗原因。在此期间,通过外科质量项目以及医疗保险和国家医疗服务体系的全国性倡议,人们做出了多项大规模努力,以确立针对老年患者的最佳治疗方案。为了解美国目前的再住院情况,我们试图按年龄报告各类手术30天再住院的发生率及原因。
我们利用美国外科医师学会国家外科质量改进计划(ACS NSQIP)2015年至2019年的数据集进行了一项回顾性研究。我们主要关注的暴露因素是年龄。患者被分为四组:18 - 49岁、50 - 64岁、65 - 74岁和75岁及以上。使用NSQIP定义的病因以及报告的国际疾病分类(ICD)- 9和ICD - 10编码评估再住院原因。我们的主要结局是30天非计划再住院的发生率,次要结局是再住院的原因。通过相对(%)和绝对(n)频率按年龄组汇总变量;使用卡方检验比较比例。由于再住院是一个事件发生时间结局,其中死亡是一个竞争事件,因此使用Gray提出的方法估计30天时再住院的累积发生率。估计非计划再住院累积发生率时采用相同策略。
共有2,798,486名患者符合纳入标准;198,542人有非计划再住院(总体为7.09%)。18 - 49岁、50 - 64岁、65 - 74岁和75岁及以上年龄组的再住院率分别为6.12%、6.99%、7.50%和9.50%。消化系统相关并发症是各年龄组再住院最常见的单一原因。手术部位感染是第二常见原因,其相对频率随年龄下降如下:21.74%、19.08%、15.09%和9.44%(p < .0001)。随着年龄增长,循环或呼吸并发症等医疗原因更为常见(分别为2.10%、4.43%、6.27%、8.86%和3.27%、4.51%、6.07%、8.11%)。
与十年前的研究相比,我们观察到老年外科患者的总体再住院率有所下降。年龄最大(≥75岁)的外科患者30天再住院率最高(9.50%)。各年龄组再住院最常见的单一原因相同,可能归因于手术(肠梗阻)。然而,老年患者中再住院的医疗原因总和更为常见;该组中手术和呼吸原因的发生率是其他原因的两倍。某些手术类型(如下肢搭桥手术)的再住院率随年龄增长的幅度高于其他手术类型(如腹外疝修补术)。未来的研究应侧重于采取干预措施,以减少医疗并发症,并进一步降低接受高风险手术的老年外科患者的术后再住院率。