Department of Integrated Health Sciences, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Department of Radiology, Kamiiida Daiichi General Hospital, Nagoya, Japan.
Nagoya J Med Sci. 2023 May;85(2):299-309. doi: 10.18999/nagjms.85.2.299.
In the evaluation of endolymphatic hydrops (EH) using magnetic resonance (MR) imaging, hybrid of reversed image of positive endolymph signal and native image of perilymph signal multiplied with heavily T2-weighted MR cisternography (HYDROPS-Mi2) imaging with the intravenous administration of a gadolinium-based contrast agent (IV-GBCA) has been utilized. Recently, MR cisternography (MRC) without GBCA has been proposed as a potential alternative method. However, the feasibility of EH evaluation by MRC without GBCA has not been established. The present study aimed to compare HYDROPS-Mi2 imaging with IV-GBCA to MRC without IV-GBCA for the evaluation of EH. In 40 ears of 20 patients with clinically suspected EH, MRC at pre-IV-GBCA and HYDROPS-Mi2 images from 4 h post-IV-GBCA were analyzed. The saccular height on the MRC (SH-MRC) was measured. The percentage of the volume of the endolymphatic space within the whole lymphatic space of the vestibule on the HYDROPS-Mi2 image (%EL-HYD) was measured. The correlation between the SH-MRC and %EL-HYD was calculated. The receiver operating characteristic (ROC) of the SH-MRC and %EL-HYD for the clinical diagnosis of EH was evaluated. The Spearman's rank correlation coefficient between the SH-MRC and %EL-HYD was 0.102. The areas under the ROC curve were 0.570 for the SH-MRC, and 0.926 for the %EL-HYD. In conclusion, there was no significant correlation between the MRC without IV-GBCA and the HYDOROPS-Mi2 with IV-GBCA in the evaluation of EH.
在使用磁共振成像（MR）评估内淋巴积水（EH）时，已经使用静脉内给予钆基造影剂（IV-GBCA）后的正内淋巴信号反转图像与外淋巴信号原始图像的混合（HYDROPS-Mi2）成像和重 T2 加权 MR 脑池造影术（MRC）进行了评估。最近，已经提出了不使用 GBCA 的 MRC 作为潜在的替代方法。然而，尚未确定不使用 GBCA 的 MRC 进行 EH 评估的可行性。本研究旨在比较 HYDROPS-Mi2 成像与 IV-GBCA 与不使用 IV-GBCA 的 MRC 用于 EH 的评估。在 20 例临床疑似 EH 的患者的 40 只耳朵中，分析了在 IV-GBCA 之前进行的 MRC 和在 IV-GBCA 后 4 小时的 HYDROPS-Mi2 图像。测量 MRC 上的囊状高度（SH-MRC）。测量 HYDROPS-Mi2 图像上整个前庭淋巴空间内内淋巴空间的体积百分比（%EL-HYD）。计算 SH-MRC 和%EL-HYD 之间的相关性。评估 SH-MRC 和%EL-HYD 对 EH 的临床诊断的 ROC。SH-MRC 和%EL-HYD 与临床诊断 EH 的相关性的 Spearman 秩相关系数为 0.102。SH-MRC 的 ROC 曲线下面积为 0.570，%EL-HYD 的 ROC 曲线下面积为 0.926。总之，在评估 EH 时，不使用 IV-GBCA 的 MRC 与使用 IV-GBCA 的 HYDOROPS-Mi2 之间没有显著相关性。
Zotero 插件
