Carme B, Laigret J
Am J Trop Med Hyg. 1979 Jan;28(1):53-5. doi: 10.4269/ajtmh.1979.28.53.
Two cases are reported which illustrate important epidemiological aspects of lymphatic filariasis--prolonged longevity of the adult parasite and the possibility of transmission by individuals with ultra-low level microfilaremia. These cases demonstrate that people can remain carriers of microfilariae in the peripheral blood for many years without reinfection, and even those with a low level microfilaremia can constitute a significant reservoir of mosquito infection. Such cases represent one of the most serious obstacles to the eradication of lymphatic filariasis in regions where control is based on chemotherapy.
报告了两例病例,这些病例说明了淋巴丝虫病的重要流行病学特征——成虫寄生虫寿命延长以及微丝蚴血症水平极低的个体传播疾病的可能性。这些病例表明,人们在没有再次感染的情况下,外周血中的微丝蚴携带者状态可维持多年,甚至微丝蚴血症水平较低的人也可能构成蚊子感染的重要传染源。在基于化疗进行疾病控制的地区,此类病例是根除淋巴丝虫病面临的最严重障碍之一。