Department of Ophthalmology, Tokyo Medical University, Tokyo, Japan.
Ocul Immunol Inflamm. 2024 Sep;32(7):1250-1256. doi: 10.1080/09273948.2023.2221741. Epub 2023 Jun 22.
To analyze radial peripapillary capillaris (RPC) and intra-papillary capillaris (IPC) using optical coherence tomography angiography (OCTA) in acute retinal necrosis (ARN) with good outcome.
RPC and IPC were analyzed by OCTA in patients diagnosed with ARN and treated with pharmacotherapy alone without surgery at the Tokyo Medical University Hospital.
A total of 13 patients were studied. Ophthalmoscopic examination showed no abnormality in the optic disc in 12 of the 13 patients. However, OCTA findings of the affected eye compared with the unaffected fellow eye revealed morphological abnormalities in RPC in nine cases (69%) and decrease in capillary network in RPC or IPC in eight cases (62%).
In ARN, RPC and IPC were impaired even in eyes that were healed with medical treatment only without requiring surgical intervention and had no abnormal findings on ophthalmoscopic examination. This result suggests the presence of some degrees of optic neuropathy even in mild cases with good visual prognosis.
分析经药物治疗（未手术）后预后良好的急性视网膜坏死（ARN）患者的视网膜神经纤维层毛细血管（RPC）和节段性内视网膜神经纤维层毛细血管（IPC）的光相干断层扫描血管造影（OCTA）。
在东京医科大学医院，对经药物治疗（未手术）的 ARN 患者进行 OCTA 检查，分析 RPC 和 IPC。
共纳入 13 例患者。13 例患者中，12 例眼底检查视盘未见异常。然而，与对侧眼相比，受影响眼的 OCTA 结果显示 9 例（69%）存在 RPC 形态异常，8 例（62%）RPC 或 IPC 中毛细血管网络减少。
即使在仅接受药物治疗、无需手术干预且眼底检查未见异常的 ARN 患者眼中，RPC 和 IPC 也存在损伤。该结果提示即使在预后良好的轻度病例中，视神经病变也存在一定程度。
