Shojaie Ali, Rota Silvia, Al Khleifat Ahmad, Ray Chaudhuri K, Al-Chalabi Ammar
Maurice Wohl Clinical Neuroscience Institute, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.
Parkinson's Foundation Centre of Excellence, King's College Hospital, London, UK.
Amyotroph Lateral Scler Frontotemporal Degener. 2023 Jun 22:1-10. doi: 10.1080/21678421.2023.2220748.
Amyotrophic lateral sclerosis and Parkinson's disease are neurodegenerative diseases of the motor system which are now recognized also to affect non-motor pathways. Non-motor symptoms have been acknowledged as important determinants of quality of life in Parkinson's disease, and there is increasing interest in understanding the extent and role of non-motor symptoms in amyotrophic lateral sclerosis. We therefore reviewed what is known about non-motor symptoms in amyotrophic lateral sclerosis, using lessons from Parkinson's disease.
肌萎缩侧索硬化症和帕金森病是运动系统的神经退行性疾病,现在人们也认识到它们会影响非运动通路。非运动症状已被公认为帕金森病患者生活质量的重要决定因素,并且人们越来越关注了解肌萎缩侧索硬化症中非运动症状的程度和作用。因此,我们借鉴帕金森病的经验,回顾了关于肌萎缩侧索硬化症中非运动症状的已知情况。