Hydroxypropyl-beta-cyclodextrin derivatives: influence of average degree of substitution on complexing ability and surface activity.

The average degree of substitution of mixtures of hydroxypropyl-beta-cyclodextrin derivatives has a large influence on the complexing abilities and physiochemical properties of the derivatives. A low degree of substitution is preferable, since these derivatives show the best complexing properties and, at the same time, low surface activities.