Suri Abhinav, Fortes Precious, Chan Benjamin H, Sachs Carolyn J
David Geffen School of Medicine at UCLA Los Angeles California USA.
Department of Pathology UCLA Health Los Angeles California USA.
Clin Case Rep. 2023 Jun 20;11(6):e7600. doi: 10.1002/ccr3.7600. eCollection 2023 Jun.
Early identification and management of chronic invasive fungal rhinosinusitis (CIFRS) is key to optimizing outcomes. A missed diagnosis can result in permanent vision loss, chronic facial pain, or death. We present a case of CIFRS and literature review.
This case report presents a 56-year-old female with CIFRS involving orbital and facial complications. The patient experienced delayed diagnosis despite multiple ED visits for sinusitis with progressive facial pain and ocular deficits not alleviated with antibiotics, emphasizing the importance of early identification and maintaining high clinical suspicion for CIFRS. Prompt recognition, initiation of antifungal therapy, and aggressive surgical debridement were crucial for preventing disease progression and improving the patient's quality of life.
慢性侵袭性真菌性鼻-鼻窦炎（CIFRS）的早期识别与处理是优化治疗结果的关键。漏诊可能导致永久性视力丧失、慢性面部疼痛或死亡。我们报告一例CIFRS病例并进行文献复习。
本病例报告介绍了一名56岁患有CIFRS且伴有眼眶和面部并发症的女性。尽管患者因鼻窦炎多次前往急诊科就诊，面部疼痛进行性加重且眼部功能缺损，使用抗生素治疗后未缓解，但仍被延迟诊断，这凸显了早期识别以及对CIFRS保持高度临床怀疑的重要性。迅速识别、启动抗真菌治疗以及积极的手术清创对于预防疾病进展和改善患者生活质量至关重要。
