免疫功能正常患者的慢性侵袭性真菌性鼻-鼻窦炎：一项回顾性病历审查
Chronic Invasive Fungal Rhinosinusitis in Immunocompetent Patients: A Retrospective Chart Review.
作者信息
Alotaibi Naif H, Omar Omar Abu, Altahan Mays, Alsheikh Haifa, Al Mana Fawziah, Mahasin Zeyad, Othman Eyas
机构信息
Department of Otolaryngology, Head and Neck Surgery and Communication Sciences, King Faisal Specialist Hospital & Research Center, Riyadh, Saudi Arabia.
College of Medicine, Alfaisal University, Riyadh, Saudi Arabia.
出版信息
Front Surg. 2020 Dec 16;7:608342. doi: 10.3389/fsurg.2020.608342. eCollection 2020.
We report cases of Chronic Invasive Fungal Sinusitis (CIFS) in patients considered as immunocompetent at tertiary care center (King Faisal Specialist Hospital), to analyze their clinical, biological, radiological features, and management. A retrospective chart review of CIFS in immunocompetent patients. The inclusion criteria as the following: immunocompetent patients of any age with histopathological findings of CIFS. Immunocompromised patients, acute Invasive Fungal Sinusitis (IFS), non-invasive fungal rhinosinusitis, and no positive histological findings were excluded. Seventeen (17) patients were included. The species isolated included: Aspergillus (most frequent) & Mucor. Surgical treatment approaches were described. Complications reported include CSF leak, blindness, recurrence, and death. Early diagnosis and management of CIFS improve clinical outcomes.
我们报告了在三级医疗中心（法赫德国王专科医院）被视为免疫功能正常的患者中慢性侵袭性真菌性鼻窦炎（CIFS）的病例，以分析其临床、生物学、放射学特征及治疗情况。对免疫功能正常患者的CIFS进行回顾性病历审查。纳入标准如下：任何年龄的免疫功能正常患者，有CIFS的组织病理学检查结果。排除免疫功能低下患者、急性侵袭性真菌性鼻窦炎（IFS）、非侵袭性真菌性鼻-鼻窦炎以及无阳性组织学检查结果的患者。共纳入17例患者。分离出的菌种包括：曲霉菌（最常见）和毛霉菌。描述了手术治疗方法。报告的并发症包括脑脊液漏、失明、复发和死亡。CIFS的早期诊断和治疗可改善临床结局。
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