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79岁人群中类风湿关节炎、骨关节炎、软骨钙质沉着症和痛风性关节炎的患病率。

Prevalence of rheumatoid arthritis, osteoarthritis, chondrocalcinosis and gouty arthritis at age 79.

作者信息

Bergström G, Bjelle A, Sorensen L B, Sundh V, Svanborg A

出版信息

J Rheumatol. 1986 Jun;13(3):527-34.

PMID:3735273
Abstract

The prevalence of rheumatic diseases was studied in representative subsamples by interview (n = 134), and by physical (n = 89) and radiographic (n = 81) examination in a representative sample of 79-year-olds in Göteborg, Sweden. The prevalence of rheumatoid arthritis (3-8 ARA criteria) was 10%. Radiographic osteoarthritis (OA) was diagnosed in wrists and/or finger joints of 65% of the probands and in knee joints of 14%. The first metacarpophalangeal (MCP I) joint was more frequently involved in males than in females (p less than 0.05). In females palpable enlargement of distal (DIP) and proximal interphalangeal finger joints correlated (p less than 0.01) to radiographic OA. The degree of heavy work in previous occupations was correlated to radiographic OA of DIP II-V in females (p less than 0.05 and of MCP I in males (p less than 0.05) but not to radiographic or clinical OA in knee joints. Symptoms of OA were reported by 6.1% in the knee and in 4.5% in hip joints. The prevalence of chondrocalcinosis averaged 15% (23% of females and 6% of males). Chondrocalcinosis of the hands occurred in 21% of females but in no males. The prevalence of hyperuricemia was 15% (women 6%, men 29%), and gouty arthritis was found in one woman.

摘要

在瑞典哥德堡对79岁老人的代表性样本进行了研究,通过访谈(n = 134)以及体格检查(n = 89)和影像学检查(n = 81)来调查风湿性疾病的患病率。类风湿关节炎(采用3 - 8条美国风湿病学会标准)的患病率为10%。在65%的先证者手腕和/或手指关节以及14%的膝关节中诊断出影像学骨关节炎(OA)。男性第一掌指关节(MCP I)受累比女性更常见(p < 0.05)。女性中,可触及的远端指间关节(DIP)和近端指间关节肿大与影像学OA相关(p < 0.01)。女性既往职业中的繁重工作程度与DIP II - V的影像学OA相关(p < 0.05),男性与MCP I的影像学OA相关(p < 0.05),但与膝关节的影像学或临床OA无关。膝关节OA症状报告率为6.1%,髋关节为4.5%。软骨钙质沉着症的患病率平均为15%(女性为23%,男性为6%)。手部软骨钙质沉着症在21%的女性中出现,但男性中未出现。高尿酸血症的患病率为15%(女性6%,男性29%)并且在一名女性中发现痛风性关节炎。

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