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冰岛髋关节骨关节炎的患病率。

Prevalence of hip osteoarthritis in Iceland.

作者信息

Ingvarsson T, Hägglund G, Lohmander L S

机构信息

General Hospital, Akureyri, Iceland.

出版信息

Ann Rheum Dis. 1999 Apr;58(4):201-7. doi: 10.1136/ard.58.4.201.

Abstract

OBJECTIVE

To assess the prevalence of primary hip osteoarthritis (OA) in Iceland. To compare the prevalence of primary hip OA in Iceland with published rates of primary hip OA for related Scandinavian populations.

METHODS

Roentgenographs were examined of 1530 Icelandic people 35 years or older (653 males, 877 females) subjected to colon radiography during the years 1990-1996. The radiographs examined represent approximately 40% of all colon radiographs taken in Iceland during this period. After exclusion of non-primary hip OA cases, the minimum hip joint space was measured with a mm ruler. Presence of hip OA was defined as a minimum joint space of 2.5 mm or less on an anteroposterior radiograph. Intraclass correlation coefficients for inter and intraobserver variability of assessment of mm joint space were 0.91 and 0.95, respectively.

RESULTS

Of the 1517 people included, 227 hips in 165 patients (77 men, 88 women) were diagnosed as having radiological primary hip OA. The mean age at colon examination for these patients was 68 (35-89) years. The overall prevalence of coxarthrosis among all examined patients 35 years and older was 10.8% (12% for men, 10% for women), rising from 2% at 35-39 years to 35.4% for those 85 years or older. If the population structure (age and sex distribution) for those older than 35 years in Iceland was used to standardise prevalence for both Iceland and south Sweden (using previously published data for south Sweden), the age and sex standardised prevalence of hip OA for those older than 35 years in Iceland was 8%, compared with 1.2% for south Sweden.

CONCLUSIONS

The prevalence of radiological primary hip OA is very high in Iceland, and in excess of fivefold higher than the prevalence found by using similar techniques in studies on related populations in southern Scandinavia. The rate difference is particularly notable for those younger than 70 years.

摘要

目的

评估冰岛原发性髋骨关节炎(OA)的患病率。将冰岛原发性髋OA的患病率与已公布的相关斯堪的纳维亚人群原发性髋OA的患病率进行比较。

方法

对1990年至1996年期间接受结肠造影的1530名35岁及以上的冰岛人(653名男性,877名女性)的X线片进行检查。所检查的X线片约占该时期冰岛所有结肠造影X线片的40%。排除非原发性髋OA病例后,用毫米尺测量最小髋关节间隙。髋OA的存在定义为前后位X线片上最小关节间隙为2.5毫米或更小。评估毫米关节间隙时,观察者间和观察者内变异性的组内相关系数分别为0.91和0.95。

结果

在纳入的1517人中,165例患者(77名男性,88名女性)的227个髋关节被诊断为患有放射学原发性髋OA。这些患者结肠检查时的平均年龄为68岁(35 - 89岁)。所有35岁及以上受检患者中髋关节炎的总体患病率为10.8%(男性为12%,女性为10%),从35至39岁时的2%上升至85岁及以上者的35.4%。如果用冰岛35岁以上人群的人口结构(年龄和性别分布)对冰岛和瑞典南部的患病率进行标准化(使用瑞典南部先前公布的数据),冰岛35岁以上人群髋OA的年龄和性别标准化患病率为8%,而瑞典南部为1.2%。

结论

冰岛放射学原发性髋OA的患病率非常高,比在斯堪的纳维亚南部相关人群研究中使用类似技术所发现的患病率高出五倍以上。对于70岁以下人群,患病率差异尤为显著。

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