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巴西高家庭农药使用史与帕金森病。

History of high household pesticide use and Parkinson's disease in Brazil.

机构信息

Universidade Federal do Pará, Instituto de Ciências Médicas, Belém, PA, Brazil.

Universidade Federal de São Paulo, Departamento de Neurologia, São Paulo, SP, Brazil.

出版信息

Parkinsonism Relat Disord. 2023 Aug;113:105493. doi: 10.1016/j.parkreldis.2023.105493. Epub 2023 Jun 19.

DOI:10.1016/j.parkreldis.2023.105493
PMID:37354828
Abstract

The prevalence of Parkinson's disease (PD) is growing worldwide and household pesticides exposure may be related to this phenomenon. We showed that individuals with high exposure to household pesticides have two times more risk of developing PD. Household pesticide exposure did not impact age at PD onset.

摘要

帕金森病(PD)的患病率在全球范围内不断增加,而家庭中接触农药可能与此现象有关。我们的研究表明,大量接触家用农药的个体患 PD 的风险增加了两倍。家庭农药暴露对 PD 发病年龄没有影响。

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引用本文的文献

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Cad Saude Publica. 2025 Apr 11;41(4):e00011424. doi: 10.1590/0102-311XEN011424. eCollection 2025.
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Modifiable risk factors associated with the risk of developing Parkinson's disease: a critical review.与帕金森病发病风险相关的可改变风险因素:一项批判性综述
Arq Neuropsiquiatr. 2025 Mar;83(3):1-10. doi: 10.1055/s-0045-1805075. Epub 2025 Mar 19.
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Temporal trend of mortality due to Parkinson's disease in older people in Brazil, 2002-2021.
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Epidemiol Serv Saude. 2024 Dec 9;33:e2024532. doi: 10.1590/S2237-96222024v33e2024532.en. eCollection 2024.
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Environmental Risk Factors for Parkinson's Disease: A Critical Review and Policy Implications.帕金森病的环境风险因素:批判性综述及政策启示
Mov Disord. 2025 Feb;40(2):204-221. doi: 10.1002/mds.30067. Epub 2024 Nov 27.
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Exposure to household pesticides and Parkinson's disease in the Parkinson's Progression Markers Initiative cohort.帕金森病进展标志物计划队列中家庭农药暴露与帕金森病的关系
Front Neurol. 2024 Aug 12;15:1411468. doi: 10.3389/fneur.2024.1411468. eCollection 2024.
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Towards a methodological uniformization of environmental risk studies in Parkinson's disease.帕金森病环境风险研究方法的统一化探索。
NPJ Parkinsons Dis. 2024 Apr 17;10(1):86. doi: 10.1038/s41531-024-00709-y.