COVID-19 大流行期间妇科癌症的发病率：荷兰基于人群的研究。

Incidence of gynaecological cancer during the COVID-19 pandemic: A population-based study in the Netherlands.

机构信息

Department of Research & Development, Netherlands Comprehensive Cancer Organisation (IKNL), Godebaldkwartier 419, 3511 DT Utrecht, the Netherlands; Department of Obstetrics and Gynecology, University Medical Center Groningen, University of Groningen, Hanzeplein 1, 9713 GZ Groningen, the Netherlands.

Department of Obstetrics and Gynecology, Leiden University Medical Center, Albinusdreef 2, 2333 ZA Leiden, the Netherlands.

出版信息

Cancer Epidemiol. 2023 Aug;85:102405. doi: 10.1016/j.canep.2023.102405. Epub 2023 Jun 20.

DOI:10.1016/j.canep.2023.102405

PMID:37356263

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10281225/

Abstract

OBJECTIVE

To study the impact of the COVID-19 pandemic and consequent lockdown on the number of diagnoses of gynaecological malignancies in the Netherlands.

METHODS

We performed a retrospective cohort study using data from the Netherlands Cancer Registry (NCR) on women of 18 years and older diagnosed with invasive endometrial, ovarian, cervical or vulvar cancer in the period 2017-2021. Analyses were stratified for age, socioeconomical status (SES) and region.

RESULTS

The incidence rate of gynaecological cancer was 67/100.000 (n = 4832) before (2017-2019) and 68/100.000 (n = 4833) during (2020) the COVID-19 pandemic. Comparing the number of diagnoses of the two periods for the four types of cancer separately showed no significant difference. During the first wave of COVID-19 (March-June 2020), a clear decrease in number of gynaecological cancer diagnoses was visible (20-34 %). Subsequently, large increases in number of diagnoses were visible (11-29 %). No significant differences in incidence were found between different age groups, SES and regions. In 2021 an increase of 5.9 % in number of diagnoses was seen.

CONCLUSION

In the Netherlands, a clear drop in number of diagnoses was visible for all four types of gynaecological cancers during the first wave, with a subsequent increase in number of diagnoses in the second part of 2020 and in 2021. No differences between SES groups were found. This illustrates good organisation of and access to health care in the Netherlands.

摘要

目的

研究 COVID-19 大流行及随之而来的封锁对荷兰妇科恶性肿瘤诊断数量的影响。

方法

我们使用荷兰癌症登记处（NCR）的数据进行了一项回顾性队列研究，该数据来自于 2017 年至 2021 年期间被诊断为浸润性子宫内膜癌、卵巢癌、宫颈癌或外阴癌的 18 岁及以上的女性。分析按年龄、社会经济地位（SES）和地区进行分层。

结果

在 COVID-19 大流行之前（2017-2019 年），妇科癌症的发病率为 67/100.000（n=4832），在 COVID-19 大流行期间（2020 年）为 68/100.000（n=4833）。将两个时期四种癌症的诊断数量进行比较，没有发现显著差异。在 COVID-19 的第一波（2020 年 3 月至 6 月）期间，妇科癌症诊断数量明显减少（20-34%）。随后，诊断数量大幅增加（11-29%）。不同年龄组、SES 和地区之间的发病率没有显著差异。2021 年，诊断数量增加了 5.9%。