The Interdisciplinary Institute of Neuroscience and Technology, School of Medicine, Zhejiang University, Hangzhou, China; MOE Frontier Science Center for Brain Science and Brain-machine Integration, Zhejiang University, Hangzhou, China.
The Interdisciplinary Institute of Neuroscience and Technology, School of Medicine, Zhejiang University, Hangzhou, China; MOE Frontier Science Center for Brain Science and Brain-machine Integration, Zhejiang University, Hangzhou, China; Key Laboratory for Biomedical Engineering of Ministry of Education, College of Biomedical Engineering & Instrument Science, Zhejiang University, Hangzhou, China.
Magn Reson Imaging. 2023 Oct;102:179-183. doi: 10.1016/j.mri.2023.06.014. Epub 2023 Jun 23.
Combining multimodal approaches with functional magnetic resonance imaging (fMRI) has catapulted the research on brain circuitries of non-human primates (NHPs) into a new era. However, many studies are constrained by a lack of appropriate RF coils. In this study, a single loop transmit and 16-channel receive array coil was constructed for brain imaging of macaques at 7 Tesla (7 T). The 16 receive channels were mounted on a 3D-printed helmet-shaped form closely fitting the macaque head, with fourteen openings arranged for multimodal devices around the cortical regions. Coil performance was evaluated by quantifying and comparing signal-to-noise ratio (SNR) maps, noise correlations, g-factor maps and flip-angle maps with a 28-channel commercial knee coil. The in vivo results suggested that the macaque coil has higher SNR in cortical regions and better acceleration ability in parallel imaging, which may benefit revealing mesoscale organizations in the brain.
将多模态方法与功能磁共振成像 (fMRI) 相结合，使非人类灵长类动物 (NHP) 的脑回路研究进入了一个新时代。然而，许多研究受到缺乏合适射频线圈的限制。在这项研究中，构建了一个用于 7 特斯拉 (7T) 猕猴脑部成像的单环发射和 16 通道接收阵列线圈。16 个接收通道安装在一个 3D 打印的头盔形状的模具上，与猕猴头部紧密贴合，在皮质区域周围有 14 个开口用于多模态设备。通过量化和比较信噪比 (SNR) 图、噪声相关性、g 因子图和翻转角图，评估线圈性能，与 28 通道商用膝关节线圈进行比较。体内实验结果表明，猕猴线圈在皮质区域具有更高的 SNR 和更好的并行成像加速能力，这可能有助于揭示大脑中的中尺度组织。
