Service d'Hématologie et Oncologie Pédiatrique, Timone Hospital, AP-HM, Marseille, France; Reverse Molecular Pharmacology in Pediatric Oncology, Centre de Recherche en Cancérologie de Marseille (CRCM), Aix-Marseille Université, CNRS, INSERM, Institut Paoli Calmettes, Marseille, France; Metronomics Global Health Initiative, Marseille, France.
Childhood Cancers and Cell Death (C3), Université Claude Bernard Lyon 1, INSERM 1052, CNRS 5286, Centre Léon Bérard, Labex DevWeCan, Centre de Recherche en Cancérologie de Lyon (CRCL), Lyon, France; Translational Research Pole in Pediatric Oncology, Centre Léon Bérard, 69008 Lyon, France.
Trends Cancer. 2023 Sep;9(9):693-696. doi: 10.1016/j.trecan.2023.05.008. Epub 2023 Jun 24.
Recently, a holistic approach to oncology that integrates a whole-body understanding of the etiology and dynamics of cancer and the development of new therapies has been proposed. Herein we discuss how this concept is also relevant to pediatric oncology, with the caveat of specificities that must be considered.
最近，提出了一种肿瘤学的整体方法，该方法将对癌症病因和动力学的整体理解与新疗法的开发相结合。在此，我们讨论了这一概念如何与儿科肿瘤学相关，同时也指出了必须考虑的具体问题。
