博来霉素与曲安奈德联合应用治疗瘢痕疙瘩和增生性瘢痕：治疗难治性瘢痕疙瘩和增生性瘢痕的有效疗法。
The combined application of bleomycin and triamcinolone for the treatment of keloids and hypertrophic scars: An effective therapy for treating refractory keloids and hypertrophic scars.
机构信息
Department of Oral and Maxillofacial Surgery, Peking University School and Hospital of Stomatology, Beijing, China.
出版信息
Skin Res Technol. 2023 Jun;29(6):e13389. doi: 10.1111/srt.13389.
BACKGROUND
Keloids and hypertrophic scars frustrate patients by the deformity of appearance and organ dysfunction. Many modalities had been tried in clinic practice, but the results are unsatisfied.
OBJECTIVE
We retrospectively analysed the combined application of bleomycin and triamcinolone for the treatment of keloids and hypertrophic scars.
METHODS
The combination of bleomycin and triamcin acetonide was applied to the treatment of keloids and hypertrophic scars, 86 cases accepted the treatment. Follow-up 2-5 years after treatment.
RESULTS
(1) The pain of scars and itching symptoms have basically subsided through treatment. (2) After drug injection treatment, the keloid began to shrink, some of the keloids disappeared. (3) Small keloids did not recur after treatment. Large keloids had local recurrence after treatment. When further treatment was given, the recurrence disappeared.
CONCLUSION
The combined application of bleomycin and triamcin acetonide can effectively cure keloids and hypertrophic scars.
背景
瘢痕疙瘩和增生性瘢痕会导致患者的外观畸形和器官功能障碍，令患者十分苦恼。临床上尝试了多种方法，但结果并不满意。
目的
我们回顾性分析了博来霉素联合曲安奈德治疗瘢痕疙瘩和增生性瘢痕的疗效。
方法
采用博来霉素联合曲安奈德治疗瘢痕疙瘩和增生性瘢痕 86 例，治疗后随访 2-5 年。
结果
（1）治疗后瘢痕疼痛和瘙痒症状基本消失。（2）药物注射治疗后，瘢痕开始缩小，部分瘢痕消失。（3）小的瘢痕疙瘩治疗后无复发，大的瘢痕疙瘩治疗后局部复发，再次治疗后复发消失。
结论
博来霉素联合曲安奈德能有效治疗瘢痕疙瘩和增生性瘢痕。
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