CHUVAC, ENVT, Université de Toulouse, Toulouse, France.
IHAP, INRAE, ENVT, Université de Toulouse, Toulouse, France.
Vet Ophthalmol. 2023 Jul;26(4):280-287. doi: 10.1111/vop.13128. Epub 2023 Jun 26.
To evaluate the clinical course and outcome of canine spontaneous chronic corneal epithelial defects (SCCEDs) treated with a combination of cotton-tip epithelial debridement (ED) and corneal thermal cautery (CTC), with or without diamond burr debridement (DBD).
Retrospective medical record review was used to identify dogs treated for SCCEDs at the Veterinary School of Toulouse between 2001 and 2021. The variables identified included signalment, history, clinical findings, previous treatments, and outcomes. Surgery was performed under manual restraint after topical anesthesia of the cornea. The outcome endpoints included healing, clearing of the cornea and complications.
Seventy-seven dogs (89 eyes) from 28 different breeds fulfilled the inclusion criteria. The mean age was 8.78 years. The overall success rate after one procedure was 65.1% with a mean healing time of 15.4 days, but 21 eyes lost to follow-up after the initial treatment, were not included in calculations. There was no significant effect of age, eye, brachycephalic conformation and previous treatments. No significant differences in healing rates were found between groups that received DBD or not. Fifteen eyes (22.7%) underwent a second procedure. Complications (corneal pigmentation, uveitis, corneal bullae, and corneal infection) were observed in 15 cases (22%), with only two cases of complicating melting ulcer.
CTC is a safe and effective treatment for SCCEDs in dogs and can be performed without general anesthesia. Additional DBD does not bring any significant value to CTC in SCCEDs. CTC could be interesting in cases where other procedures are less desirable.
评估联合使用棉拭子上皮清创术(ED)和角膜热烧蚀术(CTC)以及是否联合使用钻石磨头清创术(DBD)治疗犬自发性慢性角膜上皮缺损(SCCED)的临床过程和结果。
使用回顾性病历审查的方法,确定了 2001 年至 2021 年在图卢兹兽医学校接受 SCCED 治疗的犬。确定的变量包括品种、病史、临床发现、既往治疗和结局。手术在角膜局部麻醉下通过手动固定进行。结局终点包括愈合、角膜清洁度和并发症。
28 个不同品种的 77 只犬(89 只眼)符合纳入标准。平均年龄为 8.78 岁。单次手术后的总体成功率为 65.1%,平均愈合时间为 15.4 天,但 21 只眼在初始治疗后失访,未纳入计算。年龄、眼睛、短头型和既往治疗均无显著影响。接受或未接受 DBD 的两组之间的愈合率无显著差异。15 只眼(22.7%)接受了第二次手术。15 例(22%)出现并发症(角膜色素沉着、葡萄膜炎、角膜大疱和角膜感染),仅 2 例出现并发症性融解性溃疡。
CTC 是犬 SCCED 的一种安全有效的治疗方法,可在不进行全身麻醉的情况下进行。额外的 DBD 对 SCCED 中的 CTC 没有任何显著价值。CTC 可能对其他手术不太理想的病例有意义。