López J Francisco, Fernández Mario I, Coz Fernando
Nuffield Department of Surgical Sciences, University of Oxford, Oxford, UK.
Departamento de Urología, Clínica Alemana, Santiago, Chile.
Rev Med Chil. 2022 Oct;150(10):1370-1379. doi: 10.4067/S0034-98872022001001370.
Prostate cancer is the tumor with the highest incidence among men and one of Chile's leading causes of death.
To analyze temporal trends in prostate cancer mortality in Chile.
Mortality rates in Chile for the period between 1955 and 2019 were calculated. The number of deaths was obtained from the national demographic yearbooks and the Ministery of Health mortality registries. Population estimates from the demographic center of the Economic Commission for Latin America and the Caribbean of the United Nations were used. Chilean census population of 2017 was used as reference to calculate adjusted rates. Trends were analyzed using a join point regression.
Crude mortality rates of prostatic cancer increased between 1995 and 2012 in three different phases, namely between 1955 and 1989 with a 2.7% annual increase, between 1989 and 1996 at a 6.8% annual rate, and between 1996 to 2012 with a 2.8% annual increase. From 2012 the rate remained stable. Adjusted mortality rates increased slowly at a 1.7% rate from 1955 to 1993, accelerating between 1993 and 1996, when they increased 12.1% per year. From 1996 onwards there was a significant decrease in mortality at a 1.2% annual rate. This decrease was significant and observed within all age groups but more importantly at older ages.
Prostate cancer mortality in Chile has decreased significantly during the last two decades, like that observed in developed nations.
前列腺癌是男性中发病率最高的肿瘤，也是智利主要的死亡原因之一。
分析智利前列腺癌死亡率的时间趋势。
计算了智利1955年至2019年期间的死亡率。死亡人数来自国家人口年鉴和卫生部死亡率登记处。使用了联合国拉丁美洲和加勒比经济委员会人口统计中心的人口估计数。以2017年智利人口普查数据作为参考来计算调整率。使用连接点回归分析趋势。
前列腺癌的粗死亡率在1995年至2012年期间分三个不同阶段上升，即1955年至1989年期间每年上升2.7%，1989年至1996年期间以每年6.8%的速度上升，1996年至2012年期间每年上升2.8%。从2012年起该比率保持稳定。调整后的死亡率从1955年至1993年以1.7%的速度缓慢上升，在1993年至1996年期间加速上升，当时每年上升12.1%。从1996年起死亡率以每年1.2%的速度显著下降。这种下降在所有年龄组中都很显著，但更重要的是在老年组中。
智利前列腺癌死亡率在过去二十年中显著下降，与发达国家的情况类似。
