Department of Urology, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd., Dallas, TX, 75390-9110, USA.
Department of Obstetrics, Gynecology and Human Reproduction, Rennes University Hospital, 16 Boulevard de Bulgarie, Rennes, France.
World J Urol. 2023 Aug;41(8):2217-2223. doi: 10.1007/s00345-023-04474-0. Epub 2023 Jun 26.
To analyze trends in worldwide public interest in the treatment options for stress urinary incontinence around the latest FDA 2019 ban on vaginal mesh for prolapse.
We used the web-based tool Google Trends to analyse online searches related to the following terms: 'pelvic floor muscle exercises', 'continence pessary', 'pubovaginal slings', 'Burch colposuspension', 'midurethral slings', 'injectable bulking agents'. Data were expressed as relative search volume on a scale of 0-100. Comparisons of annual relative search volume and average annual percentage change, were analyzed to assess loss or gain of interest. Finally, we assessed the impact of the last FDA alert.
The mean annual relative search volume for midurethral slings was 20% in 2006 and significantly decreased until 8% in 2022 (p < 0.01). A regular decrease interest was recorded for autologous surgeries but a regain of interest for pubovaginal slings was registered since 2020 (+ 2.8%; p < 0.01). Conversely, a steep interest was noted for injectable bulking agents (average annual percentage change: + 4.4%; p < 0.01) and conservative therapies (p < 0.01). When trends were compared before and after the FDA 2019 alert, a lower research volume was found for midurethral slings, while a higher research volume was observed all others treatments (all p < 0.05).
The online public researches about midurethral slings have considerably decreased following warnings on the use of transvaginal mesh. There seems to be a growing interest in conservative measures, bulking agents, and recently pubovaginal slings.
分析 2019 年美国食品和药物管理局 (FDA) 禁止阴道网片用于脱垂后,全球公众对治疗压力性尿失禁的治疗选择的兴趣变化趋势。
我们使用基于网络的工具 Google Trends 分析了以下术语的在线搜索:“盆底肌肉锻炼”、“ incontinence 子宫托”、“耻骨阴道吊带”、“Burch 悬吊带”、“中尿道吊带”、“注射性填充剂”。数据以 0-100 的相对搜索量表示。通过分析年度相对搜索量和平均年变化率,评估兴趣的增减。最后,我们评估了最后一次 FDA 警报的影响。
中尿道吊带的平均年相对搜索量在 2006 年为 20%,并呈下降趋势,到 2022 年降至 8%(p<0.01)。记录到自体手术的兴趣呈常规下降趋势,但自 2020 年以来,耻骨阴道吊带的兴趣恢复(+2.8%;p<0.01)。相反,注射性填充剂(平均年变化率:+4.4%;p<0.01)和保守疗法的兴趣显著增加(p<0.01)。当比较 FDA 2019 年警报前后的趋势时,发现中尿道吊带的研究量较低,而其他所有治疗方法的研究量都较高(均 p<0.05)。
在关于阴道网片使用的警告之后,关于中尿道吊带的在线公众研究已经大大减少。人们对保守治疗、填充剂以及最近的耻骨阴道吊带的兴趣似乎有所增加。