Department of Otorhinolaryngology and Head and Neck Surgery, Kasturba Medical College, Mangalore, Manipal Academy of Higher Education, Manipal, 575001, India.
Department of Audiology and Speech Language Pathology, Kasturba Medical College, Mangalore, Manipal Academy of Higher Education, Manipal, 575001, India.
Eur Arch Otorhinolaryngol. 2023 Oct;280(10):4665-4675. doi: 10.1007/s00405-023-08065-y. Epub 2023 Jun 26.
Type 2 diabetes mellitus (T2DM) may induce micro-vascular and macro-vascular changes that can lead to neuropathic changes which may affect the auditory pathway resulting in hearing loss. The study aims to evaluate the outcome of ipsilateral and contralateral acoustic reflex (AR) parameters and reflex decay tests (RDT) in patients with T2DM, and the relationship between average AR parameters, and duration and control of T2DM.
An analytical cross-sectional study was conducted in a tertiary care setup in 126 subjects which included 42 subjects with T2DM between 30 and 60 years of age, age-matched with 84 non-diabetic subjects. The subjects were evaluated for pure tone average (PTA), speech identification score (SIS), AR parameters [acoustic reflex threshold (ART), acoustic reflex amplitude (ARA), acoustic reflex latency (ARL)] and RDT.
The subjects with T2DM showed increased PTA in both ears when compared to the subjects with no disease. No significant difference was found in the SIS between both groups. There was no significant difference in the ART and ARL between the two groups. There was a significant difference in the ipsilateral and contralateral ARA at 500 Hz, 1000 Hz and broadband noise (BBN) when compared between the diabetic and non-diabetic groups. No significant difference was found between average AR parameters and duration and control of T2DM.
T2DM increases hearing thresholds and reduces ipsilateral and contralateral AR at lower frequencies and BBN. Duration and control of T2DM do not affect the AR parameters.
2 型糖尿病（T2DM）可能引起微血管和大血管变化，导致神经病变，从而影响听觉通路，导致听力损失。本研究旨在评估 T2DM 患者同侧和对侧声反射（AR）参数和反射衰减测试（RDT）的结果，以及平均 AR 参数与 T2DM 的持续时间和控制之间的关系。
在一家三级保健机构进行了一项分析性横断面研究，纳入了 126 名受试者，其中 42 名年龄在 30 至 60 岁之间的 T2DM 患者与 84 名非糖尿病患者相匹配。对受试者进行纯音平均（PTA）、言语识别得分（SIS）、AR 参数[声反射阈值（ART）、声反射幅度（ARA）、声反射潜伏期（ARL）]和 RDT 评估。
与无疾病的受试者相比，T2DM 受试者双耳的 PTA 增加。两组间 SIS 无显著差异。两组间 ART 和 ARL 无显著差异。与非糖尿病组相比，糖尿病组在 500Hz、1000Hz 和宽带噪声（BBN）时同侧和对侧 ARA 存在显著差异。平均 AR 参数与 T2DM 的持续时间和控制之间无显著差异。
T2DM 增加了听力阈值，并降低了低频和 BBN 时的同侧和对侧 AR。T2DM 的持续时间和控制不影响 AR 参数。
