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盐酸塞利洛尔治疗血管性埃勒斯-当洛综合征患者后生活质量的改善:一例报告

Improvement in Quality of Life Following Celiprolol Hydrochloride Administration in a Patient with Vascular Ehlers-Danlos Syndrome: A Case Report.

作者信息

Shimizu Kanichiro, Kameoka Yoshihiko, Motohashi Kenji, Munetomo Yohei, Kurata Naoki, Sadaoka Shunichi

机构信息

Department of Radiology, Kashiwa Hospital, The Jikei University School of Medicine, Kashiwa, Chiba, Japan.

Department of Radiology, Kyoundo Hospital of the Sasaki Institute, Tokyo, Japan.

出版信息

Ann Vasc Dis. 2023 Jun 25;16(2):146-149. doi: 10.3400/avd.cr.22-00130.

Abstract

A 40-year-old female, who underwent transcatheter arterial embolization due to acute bleeding from an iliolumbar artery, was subsequently genetically diagnosed with vascular Ehlers-Danlos syndrome. She experienced chronic anemia for many years due to the easy bruising of her whole body. The bruising improved with oral administration of celiprolol hydrochloride. There were no cardiac or vascular events during the 7 years following the transcatheter arterial embolization. Vascular Ehlers-Danlos syndrome requires specialized treatment that is scientifically proven to prevent a major vascular event. Proactive genetic diagnosis is recommended in patients suspected of having vascular Ehlers-Danlos syndrome after careful patient interview.

摘要

一名40岁女性因髂腰动脉急性出血接受了经导管动脉栓塞术,随后经基因诊断患有血管性埃勒斯-当洛综合征。由于全身易出现瘀伤,她多年来一直患有慢性贫血。口服盐酸塞利洛尔后瘀伤情况有所改善。经导管动脉栓塞术后的7年里没有发生心脏或血管事件。血管性埃勒斯-当洛综合征需要科学证实可预防重大血管事件的专门治疗。在对疑似患有血管性埃勒斯-当洛综合征的患者进行仔细问诊后,建议进行积极的基因诊断。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bfcf/10288126/e8a10498c2f7/avd-16-2-cr.22-00130-figure01.jpg

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