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一项关于结晶尿症的研究:在实验室报告中纳入卫生饮食建议的效果。

A study of crystalluria: effectiveness of including hygienic-dietary recommendations in laboratory reports.

作者信息

Sienes Bailo Paula, Santamaría González María, Izquierdo Álvarez Silvia, Lahoz Alonso Raquel, Serrano Frago Patricia, Bancalero Flores José Luis

机构信息

Service of Clinical Biochemistry, Miguel Servet University Hospital, Zaragoza, Spain.

Service of Urology, Miguel Servet University Hospital, Zaragoza, Spain.

出版信息

Adv Lab Med. 2021 Feb 10;2(1):109-120. doi: 10.1515/almed-2020-0124. eCollection 2021 Mar.

Abstract

OBJECTIVES

To assess the effectiveness of incorporating hygienic-dietary recommendations in laboratory reports in reducing the incidence of renal colic (RC). A study was performed to compare the incidence of RC in two groups of patients who had suffered at least a crystalluria event associated with the risk of urolithiasis. Recommendations were only incorporated in the laboratory reports of one group.

METHODS

A retrospective observational study. The study sample was composed of patients who had at least an episode of crystalluria associated with a higher risk of urolithiasis. The laboratory reports of patients in Group A (n=1,115), treated in 2017, did not include any hygienic-dietary recommendations, whereas patients in Group B (n=1,692), treated in 2018, received hygienic-dietary recommendations through their laboratory reports. χ and Mann-Whitney U test were used to assess differences based on sex, age, and type of urinary crystals.

RESULTS

The incidence of RC was 2.02 times higher in group A (2.24%) than in group B (1.12%). No significant differences were observed in the incidence of RC based on the type of urinary crystal. The incidence of RC was substantially higher in patients who suffered at least an event of crystalluria associated with a higher risk for urolithiasis as compared to the general population during the same period (0.46%, consistently with the incidence rates reported in the literature).

CONCLUSIONS

The incorporation of messages alerting on the risk of urolithiasis and the inclusion of hygienic-dietary recommendations in laboratory reports may be useful for reducing the incidence of RC.

摘要

目的

评估在实验室报告中纳入卫生饮食建议对降低肾绞痛(RC)发病率的有效性。开展了一项研究,比较两组至少发生过一次与尿路结石风险相关的结晶尿事件的患者的肾绞痛发病率。建议仅纳入其中一组患者的实验室报告中。

方法

一项回顾性观察研究。研究样本由至少发生过一次与较高尿路结石风险相关的结晶尿事件的患者组成。2017年接受治疗的A组(n = 1115)患者的实验室报告未包含任何卫生饮食建议,而2018年接受治疗的B组(n = 1692)患者通过其实验室报告获得了卫生饮食建议。采用χ检验和曼-惠特尼U检验评估基于性别、年龄和尿结晶类型的差异。

结果

A组的肾绞痛发病率(2.24%)比B组(1.12%)高2.02倍。基于尿结晶类型,未观察到肾绞痛发病率的显著差异。与同期普通人群相比,至少发生过一次与较高尿路结石风险相关的结晶尿事件的患者的肾绞痛发病率显著更高(0.46%,与文献报道的发病率一致)。

结论

在实验室报告中纳入关于尿路结石风险的警示信息以及卫生饮食建议可能有助于降低肾绞痛的发病率。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1368/10197420/01b5a81708e6/j_almed-2020-0124_fig_001.jpg

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