Fabian Iu, Gorak Ia, Taborskiĭ Ia
Kardiologiia. 1986 May;26(5):80-5.
Hemodynamic studies at rest and under volumetric loads were carried out in 10 dogs before and after the ligation of the right coronary artery with the closed pericardium. The ligation of the right coronary artery resulted in hemodynamic signs of depressed right-ventricular function: decreased systolic blood pressure and elevated end diastolic pressure, combined with the functional curve's downward shift to the right. Total cardiac performance (minute output and mean systemic flow pressure) was also reduced. It is suggested that depressed right-ventricular myocardial systolic function in infarction may be important for the development of the clinical low minute volume syndrome. Its pathophysiological mechanism and clinical implications are discussed.
在10只狗身上，于封闭心包状态下，对右侧冠状动脉结扎前后静息及容量负荷状态下的血流动力学进行了研究。右侧冠状动脉结扎导致右心室功能降低的血流动力学征象：收缩压降低，舒张末期压力升高，同时功能曲线向右下移位。总心功能（每分输出量和平均体循环流压）也降低。提示梗死时右心室心肌收缩功能降低可能对临床低每分容量综合征的发生发展具有重要意义。文中讨论了其病理生理机制及临床意义。
