Orlova N N, Bratus' V V
Kardiologiia. 1986 May;26(5):85-8.
Relationship between the realization of the coronary dilatation reserve and cardiac contractility was investigated in acute dog experiments with the intact thoracic cage under partially limited and rationed flow through a major coronary artery (a 30-minute 70% reduction), and during subsequent reperfusion. Limited coronary flow was seen in combination with moderately depressed cardiac contractility that did not improve significantly during the reperfusion period of equal duration. Inadequate realization of the coronary dilatation reserve that fails to restore the balance between blood supply and myocardial oxygen requirement may be a cause of incomplete recovery during the early reperfusion period.
在急性犬实验中,在完整胸廓下,通过一条主要冠状动脉进行部分受限和定量血流(减少70%,持续30分钟)以及随后的再灌注过程中,研究了冠状动脉扩张储备的实现与心脏收缩力之间的关系。观察到冠状动脉血流受限与心脏收缩力适度降低同时出现,且在相同持续时间的再灌注期内未显著改善。冠状动脉扩张储备未能充分实现,无法恢复血液供应与心肌需氧量之间的平衡,这可能是早期再灌注期恢复不完全的一个原因。