Tygesen Marie Louise Boeg, Maigaard Katrine, Hagstrøm Julie, Skov Liselotte, Plessen Kerstin Jessica, Debes Nanette Marinette Monique
Child and Adolescent Mental Health Center, Mental Health Services, Gentofte, Capital Region of Denmark.
Department of Pediatrics, Herlev Hospital, University of Copenhagen, Copenhagen, Denmark.
Scand J Child Adolesc Psychiatr Psychol. 2023 Jun 22;11(1):60-68. doi: 10.2478/sjcapp-2023-0006. eCollection 2023 Jan.
The exact etiology of Tourette Syndrome (TS) remains unclear, making the search for impaired neuropsychological functions possibly connected to the underlying cause of TS as important as it is challenging. One neuropsychological domain of interest is fine motor skills.
This study compared fine motor skill performance on the Purdue Pegboard Task (PPT) in 18 children with TS, 24 unaffected first-degree siblings and 20 controls. A set of screening questionnaires was administered to determine comorbid psychiatric illness.
Children with TS, their siblings and controls did not differ significantly in fine motor skills as measured with the PPT. Performance on the PPT was not correlated with tic severity; however, we found an inverse correlation with severity of attention-deficit/hyperactivity disorder (ADHD) symptoms, as assessed by parent reported ADHD symptoms. Children with TS were found to have significantly higher parent reported ADHD symptoms compared to controls, yet only two out of the 18 participants had been diagnosed with ADHD.
This study suggests that fine motor skill impairment in children with TS may be more strongly correlated with comorbid ADHD than to TS and tics.
抽动秽语综合征（TS）的确切病因仍不清楚，这使得寻找可能与TS潜在病因相关的神经心理功能受损情况既重要又具有挑战性。一个受关注的神经心理领域是精细运动技能。
本研究比较了18名TS患儿、24名未受影响的一级亲属和20名对照组在普渡钉板任务（PPT）中的精细运动技能表现。使用了一组筛查问卷来确定共病的精神疾病。
TS患儿、他们的兄弟姐妹和对照组在通过PPT测量的精细运动技能方面没有显著差异。PPT表现与抽动严重程度无关；然而，我们发现与父母报告的注意力缺陷/多动障碍（ADHD）症状严重程度呈负相关。与对照组相比，TS患儿的父母报告的ADHD症状明显更高，但18名参与者中只有两人被诊断患有ADHD。
本研究表明，TS患儿的精细运动技能损害可能与共病的ADHD比与TS和抽动更密切相关。
