Munsamy Alvin Jeffrey, Ngema Andile, Bisetty Seyuri, Lushaba S'fundo, Mayaba Nomvelo, Mthiyane Bongakonke, Nyathi Nombuso, Thabethe Amen
University of KwaZulu-Natal, ZA.
Br Ir Orthopt J. 2023 Jun 20;19(1):52-63. doi: 10.22599/bioj.303. eCollection 2023.
The study sought to compare the normative amplitude of accommodation (AoA) in school-going children from studies in the 21st century, based on pooled estimates from meta-analyses, to assess their agreement to Hofstetter's average formula.
A PRISMA checklist was used to conduct the review. PubMed, EBSCOHOST and Medline electronic databases were employed, and hand searching resulting in 259 studies up to July 2021. After title and abstract screening, 12 studies underwent full-text screening, resulting in five studies for data extraction. The pooled effect size was determined using meta-analyses for sub-groups by age. A one-sample t-test was used to compare the pool-effect size estimates (monocular) to the expected AoA from Hofstetter's average formula.
The comparison of pool estimates of AoA with the expected Hofstetter's average formula for the age sub-groups showed significant mean differences for: six-year olds: mean difference of -3.4 D (95% CI: -5.85; -1.04; p = 0.025); nine-year olds: mean difference of -4.1D (95% CI: -7.95; -0.20; p = 0.043); ten-year olds: mean difference of -4.6D (95% CI: -8.57; -0.54; p = 0.035) and 11-year olds: mean difference of -5.2 D (95% CI: -8.06; -2.40; p = 0.005). According to the quality assessment tool used, overall, the body of evidence was of good quality.
Hofstetter's prediction of normative amplitude of accommodation today may over-estimate for children aged six, nine, 10 and 11. The observed under-accommodation estimates from these comparisons may warrant consideration in assessing for a larger lag of accommodation in these age groups with myopia or pre-myopia, as part of the surveillance for progression.
本研究旨在根据荟萃分析的汇总估计值,比较21世纪研究中在校儿童的调节幅度规范值(AoA),以评估其与霍夫施泰特平均公式的一致性。
使用PRISMA清单进行综述。利用PubMed、EBSCOHOST和Medline电子数据库,并通过手工检索,截至2021年7月共获得259项研究。经过标题和摘要筛选后,12项研究进行了全文筛选,最终有5项研究用于数据提取。通过对年龄亚组进行荟萃分析来确定合并效应大小。使用单样本t检验将合并效应大小估计值(单眼)与霍夫施泰特平均公式的预期调节幅度进行比较。
年龄亚组的调节幅度合并估计值与预期的霍夫施泰特平均公式的比较显示,六岁儿童存在显著平均差异:平均差异为-3.4 D(95%置信区间:-5.85;-1.04;p = 0.025);九岁儿童:平均差异为-4.1D(95%置信区间:-7.95;-0.20;p = 0.043);十岁儿童:平均差异为-4.6D(95%置信区间:-8.57;-0.54;p = 0.035);十一岁儿童:平均差异为-5.2 D(95%置信区间:-8.06;-2.40;p = 0.005)。根据所使用的质量评估工具,总体而言,证据质量良好。
霍夫施泰特目前对调节幅度规范值的预测可能高估了六岁、九岁、十岁和十一岁儿童的情况。这些比较中观察到的调节不足估计值可能值得在评估这些近视或近视前期年龄组更大的调节滞后时予以考虑,作为进展监测的一部分。