Dos Santos Neto Elizeu Pereira, de Sousa Ícaro Araújo, Veras Arthur de Oliveira, de Barros-Araújo Marx Lima, Ricarte Irapuá Ferreira, Pontes-Neto Octávio Marques
Institute of Radiology, University of São Paulo School of Medicine, Hospital das Clínicas, São Paulo, SP, Brazil.
Neurologist and Interventional Neuroradiologist, Hospital Santa Maria, Teresina, PI, Brazil.
Front Neurol. 2023 Jun 8;14:1165484. doi: 10.3389/fneur.2023.1165484. eCollection 2023.
The effectiveness of endovascular thrombectomy in patients presenting low National Institutes of Health Stroke Scale (NIHSS) scores remains controversial, and the acquisition of additional evidence is required to refine the selection of candidates who may benefit the most from this therapeutic modality. In this study, we present the case of a 62-year-old individual, with left internal carotid occlusion stroke and low NIHSS, who had compensatory collateral flow from Willis polygon via the anterior communicating artery. The patient subsequently exhibited neurological deterioration and collateral flow failure from Willis polygon, indicating the need for urgent intervention. The study of collaterals in patients with large vessel occlusion stroke has garnered considerable attention, with research suggesting that individuals with low NIHSS scores and poor collateral profiles may be at a heightened risk of early neurological deterioration. We postulate that such patients may derive significant benefits from endovascular thrombectomy, and may posit that an intensive transcranial Doppler monitoring protocol could facilitate the identification of suitable candidates for such intervention.
血管内血栓切除术对美国国立卫生研究院卒中量表(NIHSS)评分较低的患者的有效性仍存在争议,需要获取更多证据以优化对可能从这种治疗方式中获益最大的候选者的选择。在本研究中,我们报告了一例62岁的患者,患有左侧颈内动脉闭塞性卒中且NIHSS评分较低,其通过前交通动脉从Willis环获得代偿性侧支血流。该患者随后出现神经功能恶化以及Willis环侧支血流衰竭,提示需要紧急干预。对大血管闭塞性卒中患者侧支循环的研究已引起相当大的关注,研究表明,NIHSS评分较低且侧支循环状况较差的个体可能早期神经功能恶化风险更高。我们推测这类患者可能从血管内血栓切除术中获得显著益处,并认为强化经颅多普勒监测方案可能有助于识别适合此类干预的候选者。