Burns E R, Billett H H, Frater R W, Sisto D A
J Thorac Cardiovasc Surg. 1986 Aug;92(2):310-2.
To determine whether the preoperative bleeding time, the most reliable indicator of in vivo platelet dysfunction, can prognosticate excessive postoperative hemorrhage and, hence, the need for infusion of platelet concentrations, we studied blood loss versus bleeding time in 43 patients undergoing coronary bypass grafting. There was no correlation between bleeding time and either fall in hemoglobin level (r = 0.04) or chest tube drainage (r = 0.004). In addition, bleeding time did not correlate with the number of units of platelet concentrate (r = 0.12) or packed red cells (r = 0.2) infused. The bleeding time, which has been recommended as an essential screening test before all cardiopulmonary bypass procedures, need not be performed as a preoperative screen in otherwise healthy patients with no history of bleeding abnormalities and a normal coagulation profile.
为了确定术前出血时间(体内血小板功能最可靠的指标)能否预测术后过度出血,以及由此是否需要输注血小板浓缩液,我们研究了43例接受冠状动脉搭桥术患者的失血量与出血时间之间的关系。出血时间与血红蛋白水平下降(r = 0.04)或胸管引流量(r = 0.004)均无相关性。此外,出血时间与输注的血小板浓缩液单位数(r = 0.12)或浓缩红细胞单位数(r = 0.2)也无相关性。出血时间曾被推荐为所有体外循环手术前的必要筛查试验,但对于没有出血异常病史且凝血指标正常的健康患者,无需将其作为术前筛查项目。