Fucà Elisa, Costanzo Floriana, Celestini Laura, Galassi Paolo, Villani Alberto, Valentini Diletta, Vicari Stefano
Child and Adolescent Neuropsychiatry Unit, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy.
Pediatric Unit, Pediatric Emergency Department, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy.
Front Psychiatry. 2023 Jun 9;14:1193176. doi: 10.3389/fpsyt.2023.1193176. eCollection 2023.
Individuals with Down syndrome (DS) are at risk of developing sleep problems. In spite of the well-established knowledge on the presence of sleep difficulties in DS individuals and the associated emotional and behavioral problems, less is known about the possible differences in the kind of associations between sleep and emotional/behavioral problems across different age ranges.
In this retrospective study, we included 289 participants with DS aged 6-18 years with the aims to explore differences in the distribution of sleep problems between specific age groups (school age vs. adolescence) and to identify specific age-based associations between sleep problems and emotional/behavioral problems.
Some differences in the distribution of sleep problems have emerged between age groups. Moreover, differences in the patterns of association between emotional/behavioral difficulties and sleep problems-in particular, sleep-related breathing difficulties and parasomnias-have been observed. However, sleep-wake transition disorders and excessive daily somnolence appear to be related to emotional and behavioral problems (both internalizing and externalizing), in general, across school age and adolescence.
These results remark the importance of appropriate neuropsychiatric and psychological evaluation taking into account the age-specific needs and features of individuals with DS.
唐氏综合征(DS)患者有出现睡眠问题的风险。尽管对于DS患者存在睡眠困难以及相关的情绪和行为问题已有充分的认识,但对于不同年龄范围内睡眠与情绪/行为问题之间关联类型的可能差异,人们了解得较少。
在这项回顾性研究中,我们纳入了289名6至18岁的DS患者,旨在探讨特定年龄组(学龄期与青春期)之间睡眠问题分布的差异,并确定睡眠问题与情绪/行为问题之间基于年龄的特定关联。
年龄组之间在睡眠问题分布上出现了一些差异。此外,还观察到情绪/行为困难与睡眠问题之间的关联模式存在差异,特别是与睡眠相关的呼吸困难和异态睡眠。然而,一般而言,在学龄期和青春期,睡眠 - 觉醒转换障碍和每日过度嗜睡似乎与情绪和行为问题(内化和外化)都有关。
这些结果表明,考虑到DS患者的年龄特异性需求和特征进行适当的神经精神和心理评估非常重要。