AlKhalifah Zainab, Alzahrani Amal, Abdu Shahad, Kabbarah Ammar, Kamal Omar, Althoubaity Fatma
Faculty of Medicine, King Abdulaziz University.
Department of Surgery, King Abdulaziz University Hospital, Jeddah, Saudi Arabia.
Ann Med Surg (Lond). 2023 May 3;85(6):2749-2755. doi: 10.1097/MS9.0000000000000720. eCollection 2023 Jun.
Laparoscopic cholecystectomy (LC) is the gold standard treatment for gallstones. However, it is associated with several complications. No previous studies have investigated LC complications and their associated risk factors in the western region of Saudi Arabia.
We aimed to identify the risk factors for postoperative complications (POCs) of LC at a tertiary institute in Jeddah, Western Saudi Arabia.
This retrospective study was conducted between June 2021 and August 2021 among patients who underwent LC at a tertiary centre in Jeddah, Saudi Arabia.
Records of 596 patients were reviewed, and 510 patients were included in the final analysis after applying the exclusion criteria. Data were collected from hospital medical records. tests and independent tests were used to analyse categorical and continuous variables, respectively. The Mann-Whitney test was used for nonparametric data. Multivariate regression analysis was used to adjust the values to determine the most strongly and independently associated risk factors.
Our data showed that the overall incidence of intraoperative complications (IOCs) was 10.8%. The most common complications were gallbladder perforation (=28, 5.5%), bile leakage (=25, 4.9%), and bleeding (=15, 2.9%). POCs occurred in 11% of the patients; the majority complained of abdominal pain (=36, 6.9%), had elevated liver function tests (=14, 2.7%), and retained stones (=11, 2.2%). Acute cholecystitis, overweight, diabetes, and male sex were significant predictors of IOC, POC, and conversion to open cholecystectomy (<0.05).
LC complications have a multifactorial aetiology. Patient awareness of all possible IOCs is fundamental. The improved skill and experience of the surgical team can mitigate serious complications.
腹腔镜胆囊切除术（LC）是胆结石的金标准治疗方法。然而，它会引发多种并发症。此前尚无研究在沙特阿拉伯西部地区调查LC并发症及其相关危险因素。
我们旨在确定沙特阿拉伯西部吉达市一家三级医疗机构中LC术后并发症（POC）的危险因素。
本回顾性研究于2021年6月至2021年8月期间在沙特阿拉伯吉达市一家三级中心接受LC手术的患者中进行。
回顾了596例患者的记录，应用排除标准后，510例患者纳入最终分析。数据从医院病历中收集。分别使用检验和独立检验分析分类变量和连续变量。Mann-Whitney检验用于非参数数据。多因素回归分析用于调整值以确定最强且独立相关的危险因素。
我们的数据显示术中并发症（IOC）的总体发生率为10.8%。最常见的并发症是胆囊穿孔（=28，5.5%）、胆漏（=25，4.9%）和出血（=15，2.9%）。11%的患者发生了POC；大多数患者主诉腹痛（=36，6.9%）、肝功能检查结果升高（=14，2.7%）和结石残留（=11，2.2%）。急性胆囊炎、超重、糖尿病和男性是IOC、POC以及转为开腹胆囊切除术的显著预测因素（<0.05）。
LC并发症有多种病因。患者对所有可能的IOC有所了解至关重要。手术团队技术和经验的提高可减轻严重并发症的发生。
