Rahat Manahil, Saqib Muhammad, Ahmed Muhammad, Suleman Muhammad, Ismail Syed M, Mumtaz Hassan, Khalid Hamna
Armed Forces Institute of Pathology, Rawalpindi.
Khyber Medical College, Peshawar.
Ann Med Surg (Lond). 2023 May 3;85(6):2756-2760. doi: 10.1097/MS9.0000000000000741. eCollection 2023 Jun.
Approximately 50% of the human population on the Earth is estimated to be affected by the bacterium . which causes disease manifestations ranging from peptic ulcer disease to chronic gastritis to gastric cancer. It has been a struggle to contain this bacterium using conventional antibiotics due to rising antimicrobial resistance, which has made its eradication an even bigger challenge. Due to this major issue, scientists have ventured to use alternative approaches to bring about the eradication of colonization.
The main aim of this review was to update previous studies that investigated periodontal therapy's effect on eradication.
A systematic electronic search of the currently available research was conducted to identify all the relevant trials and original studies that compared the clinical effect of periodontal therapy in conjunction with eradication therapy.
The newly updated review of the literature did not change the conclusion previously reached and instead reinforced the fact with more power and more recent studies that the addition of periodontal therapy to eradication therapy for is superior to the use of eradication therapy alone for .
The addition of periodontal therapy to the standard eradication therapy may be a clinically viable option and pave the way for tackling the burden as well as aiding in the prevention of antimicrobial resistance to an extent, along with immensely increasing the efficacy of the standard eradication therapy for that is currently in use around the world.
据估计，地球上约50%的人口受到这种细菌的影响。这种细菌会引发从消化性溃疡病到慢性胃炎再到胃癌等一系列疾病表现。由于抗菌耐药性不断上升，使用传统抗生素控制这种细菌一直是一项艰巨的任务，这使得根除该细菌成为一个更大的挑战。由于这个主要问题，科学家们已尝试使用替代方法来实现根除该细菌的定植。
本综述的主要目的是更新之前研究牙周治疗对根除该细菌效果的研究。
对当前可用的研究进行系统的电子检索，以识别所有比较牙周治疗联合根除治疗临床效果的相关试验和原始研究。
新更新的文献综述并未改变之前得出的结论，相反，通过更有力和更新的研究强化了这一事实，即对于该细菌，在根除治疗中添加牙周治疗优于单独使用根除治疗。
在标准根除治疗中添加牙周治疗可能是一种临床上可行的选择，为应对该细菌负担铺平道路，并在一定程度上有助于预防抗菌耐药性，同时极大地提高目前在全球使用的该细菌标准根除治疗的疗效。
