Dev Santosh, Yadav Radheshyam, Sah Birendra, Sah Ashok Kumar, Ghimire Bikal, Shah Jayant Kumar
Department of General Surgery.
Maharajgunj Medical Campus, Institute of Medicine, Tribhuvan University Teaching Hospital.
Ann Med Surg (Lond). 2023 May 8;85(6):3098-3101. doi: 10.1097/MS9.0000000000000791. eCollection 2023 Jun.
Hepatogastric fistula following pyogenic liver abscess (PLA) is a rare and fatal complication, and only a handful of cases have been reported without co-existing comorbidities of Brugarda syndrome.
A 22-year-old male presented to the emergency room with a known case of Brugarda pattern ECG with chief complaints of on-and-off abdominal pain and fever for 2 weeks and shortness of breath for one day. On evaluation, echocardiography showed a clot in the inferior vena cava (IVC) and right atrium (RA), and on computed tomography scan of the abdomen revealed a liver abscess with transmural gastric perforation. During, an exploratory laparotomy where a fistula joining the left lobe of the liver and stomach was detected, and an emergency excision was done. The patient was shifted to the ICU and later developed septic shock, which was managed medically.
Usually, thrombosis of the portal vein and the hepatic vein is a very common complication of a PLA but vascular complications like IVC, RA thrombosis, and hepatogastric fistula have been reported rarely. Our case is peculiar hepatogastric fistulization along with IVC/RA clots in a patient with Brugarda pattern ECG. The typical clinical manifestation of a patient with hepatogenic fistula is absent in our patient and presented with an on-off type of fever, epigastric pain, and shortness of breath and was managed surgically.
Hepatogasric fistula, thrombosis of the IVC, and RA are a rare complications of PLA. The patient with Brugarda syndrome is at high risk as its clinical manifestation gets exaggerated during sepsis.
化脓性肝脓肿(PLA)后发生肝胃瘘是一种罕见且致命的并发症,仅有少数病例报道,且不存在并存的 Brugada 综合征合并症。
一名 22 岁男性因已知 Brugada 型心电图被送往急诊室,主要症状为间断性腹痛和发热 2 周,以及气短 1 天。评估时,超声心动图显示下腔静脉(IVC)和右心房(RA)有血栓,腹部计算机断层扫描显示肝脓肿伴胃壁全层穿孔。在剖腹探查术中,发现了连接肝左叶和胃的瘘管,并进行了紧急切除。患者被转入重症监护病房,后来发生感染性休克,经药物治疗。
通常,门静脉和肝静脉血栓形成是 PLA 非常常见的并发症,但像 IVC、RA 血栓形成以及肝胃瘘这样的血管并发症很少被报道。我们的病例很特殊,是一名有 Brugada 型心电图的患者出现肝胃瘘并伴有 IVC/RA 血栓。我们的患者没有肝源性瘘管患者的典型临床表现,而是表现为间断性发热、上腹部疼痛和气短,并接受了手术治疗。
肝胃瘘、IVC 和 RA 血栓形成是 PLA 的罕见并发症。患有 Brugada 综合征的患者风险很高,因为其临床表现在脓毒症期间会加重。