Department of Internal Medicine, Hôpital de la Croix-Rousse, Hospices Civils de Lyon, Université Claude Bernard Lyon 1, Lyon, France.
Laboratoire UMR-CNRS 5303: Laboratory of Tissue Biology and Therapeutic Engineering, Institute of Biology and Protein Chemistry, Lyon, France.
Ocul Immunol Inflamm. 2024 Feb;32(2):161-167. doi: 10.1080/09273948.2023.2226203. Epub 2023 Jun 26.
To evaluate the contribution of chest X-ray and chest CT for the diagnosis of sarcoid uveitis.
Retrospective study on consecutive patients with uveitis of unknown etiology, who underwent both chest X-ray and CT during uveitis diagnosis workup in a tertiary French university hospital.
A total of 914 patients were included. Systemic sarcoidosis was identified in 23.1%. The probability of discordance between chest X-ray and CT increased with age at diagnosis ( < 0.001). In patients 30 years of age and younger, the probability of discordance was 5% or less, and 0.8% if the ACE level was normal. After 78.3 years of age, the probability of discordance was 20% or more.
We recommend not to perform CT in patients under 30 years of age with a normal chest X ray and ACE level, and suggest performing chest CT first in the elderly.
评估胸部 X 光和胸部 CT 对结节病性葡萄膜炎诊断的贡献。
回顾性研究连续患有不明原因葡萄膜炎的患者,这些患者在法国一所三级大学医院的葡萄膜炎诊断过程中同时接受了胸部 X 光和 CT 检查。
共纳入 914 例患者。诊断时发现系统性结节病 23.1%。胸部 X 光和 CT 之间不一致的概率随诊断年龄的增加而增加( < 0.001)。在 30 岁及以下的患者中,不一致的概率低于 5%,如果 ACE 水平正常则为 0.8%。在 78.3 岁以上的患者中,不一致的概率为 20%或更高。
我们建议对于年龄在 30 岁以下且胸部 X 光和 ACE 水平正常的患者,不进行 CT 检查,而建议在老年患者中首先进行胸部 CT 检查。