Tennessee Valley Healthcare System, United States; Vanderbilt University Medical Center, United States.
Kings College London, United States; Florida State University, United States.
J Affect Disord. 2023 Oct 1;338:414-421. doi: 10.1016/j.jad.2023.06.047. Epub 2023 Jun 24.
Suicide is a widespread public health concern, including among military Veterans. Traumatic brain injuries (TBIs) and lack of social integration have both been shown to increase risk for suicidality, an outcome that includes, among other suicide-related variables, suicidal ideation, suicide attempts, and suicide death. Interestingly, TBIs have also been identified as a risk factor for social integration problems. In this cross-sectional study we investigated associations between TBI, social integration, and suicidality. Additionally, mediation analysis was used to test whether social integration mediated the association between TBI and suicidality. A sample of 1469 military Veterans (male, n = 1004, 67.2 %; female, n = 457, 32.3 %; transgender/non-binary/prefer not to say, n = 8, 0.5 %) completed an online survey as part of the Military Health and Well-Being Project. TBI was negatively associated with social integration (r = -0.084, p < .001) and positively with suicidality (r = 0.205, p < .001). Social integration was negatively associated with suicidality (r = -0.161, p < .001). Finally, social integration partially mediated the relationship between TBI and social integration (B = 0.121, 95 % CI [0.031-0.23]). This work shows that in the context of TBI, lack of social integration may promote suicidality. It provides support for many theories of suicide which propose social problems as a risk factor of suicide-related outcomes. It further highlights social integration as potential fodder for novel interventions for suicidality, an approach that would have transtheoretical support.
自杀是一个普遍存在的公共卫生问题,包括退伍军人。创伤性脑损伤(TBI)和缺乏社会融合都已被证明会增加自杀倾向的风险,自杀倾向的结果包括自杀意念、自杀企图和自杀死亡等其他与自杀相关的变量。有趣的是,TBI 也被确定为社会融合问题的一个风险因素。在这项横断面研究中,我们调查了 TBI、社会融合和自杀倾向之间的关联。此外,还进行了中介分析,以检验社会融合是否在 TBI 和自杀倾向之间的关联中起中介作用。一个由 1469 名退伍军人(男性,n=1004,67.2%;女性,n=457,32.3%;跨性别/非二元/未说明,n=8,0.5%)组成的样本完成了一项在线调查,作为军事健康和幸福项目的一部分。TBI 与社会融合呈负相关(r=-0.084,p<0.001),与自杀倾向呈正相关(r=0.205,p<0.001)。社会融合与自杀倾向呈负相关(r=-0.161,p<0.001)。最后,社会融合部分中介了 TBI 和社会融合之间的关系(B=0.121,95%置信区间[0.031-0.23])。这项工作表明,在 TBI 的背景下,缺乏社会融合可能会促进自杀倾向。它为许多自杀理论提供了支持,这些理论提出社会问题是自杀相关结果的一个风险因素。它进一步强调了社会融合作为自杀干预的潜在新方法,这种方法将具有跨理论支持。