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加拿大艾伯塔省新冠疫情期间主要不良心脏事件及医疗保健利用情况的趋势

Trends in major adverse cardiac events and healthcare utilization during the COVID-19 pandemic in Alberta, Canada.

作者信息

Mackinnon Erin S, Anderson Todd, Raggi Paulo, Gregoire Jean, Wani Rajvi J, Packalen Millicent S, Graves Erin, Ekwaru Paul, McMullen Suzanne, Goodman Shaun G

机构信息

Amgen Canada Inc., Mississauga, Ontario, Canada.

University of Calgary, Calgary, Alberta, Canada.

出版信息

CJC Open. 2023 Jun 22;5(10):719-27. doi: 10.1016/j.cjco.2023.06.004.

Abstract

BACKGROUND

Atherosclerotic cardiovascular disease (ASCVD) is a leading cause of morbidity and mortality in Canada. The COVID-19 pandemic altered the usual care of ambulatory and acute cardiac patients. This study aimed to describe ASCVD-related clinical outcomes and healthcare resource utilization (HCRU) patterns during the coronavirus disease 2019 (COVID-19) pandemic in Alberta, Canada, relative to the three preceding years.

METHODS

A repeated cross-sectional study design was conducted over three-month periods using administrative health data between March 15, 2017, and March 14, 2021. ASCVD-related clinical outcomes included major adverse cardiovascular events (MACE) endpoints. HCRU was assessed through general practitioner and other healthcare professional visits (including telehealth claims) for ASCVD events, emergency department visits, ASCVD diagnostic imaging tests, laboratory tests, and hospital length of stay.

RESULTS

Relative to the control year period (March to June 2019) ASCVD-related events (i.e., hospitalizations, emergency department (ED) visits and physician office visits) declined by 23% during the three-months COVID-19 period (March to June 2020). Acute declines were not sustained following June 2020. In contrast, in-patient mortality rates involving a primary MACE endpoint increased from March to June 2020 COVID-19 period.

CONCLUSIONS

This study demonstrates the COVID-19 pandemic and corresponding public health restrictions impacted ASCVD-related care. While many clinical outcomes returned to pre-pandemic levels at the end of the observation period, our results suggest that patients' HCRU declined, which could lead to further CV events and mortality. Understanding the impact of COVID-19 restrictions on ASCVD-related care may help improve healthcare resiliency.

摘要

背景

动脉粥样硬化性心血管疾病(ASCVD)是加拿大发病和死亡的主要原因。2019冠状病毒病(COVID-19)大流行改变了门诊和急性心脏病患者的常规护理。本研究旨在描述加拿大艾伯塔省2019冠状病毒病(COVID-19)大流行期间相对于前三年的ASCVD相关临床结局和医疗资源利用(HCRU)模式。

方法

采用重复横断面研究设计,在2017年3月15日至2021年3月14日期间使用行政卫生数据,每三个月进行一次研究。ASCVD相关临床结局包括主要不良心血管事件(MACE)终点。通过全科医生和其他医疗专业人员对ASCVD事件的就诊(包括远程医疗索赔)、急诊科就诊、ASCVD诊断成像检查、实验室检查和住院时间来评估HCRU。

结果

与对照年份期间(2019年3月至6月)相比,在COVID-19期间的三个月(2020年3月至6月),ASCVD相关事件(即住院、急诊科(ED)就诊和医生办公室就诊)下降了23%。2020年6月之后,急性下降趋势并未持续。相比之下,在2020年3月至6月COVID-19期间,涉及主要MACE终点的住院死亡率有所上升。

结论

本研究表明,COVID-19大流行及相应的公共卫生限制措施影响了ASCVD相关护理。虽然许多临床结局在观察期结束时恢复到了大流行前的水平,但我们的结果表明患者的HCRU下降,这可能导致进一步的心血管事件和死亡。了解COVID-19限制措施对ASCVD相关护理的影响可能有助于提高医疗保健的恢复能力。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9cd1/10591130/d8645fd25d43/gr1.jpg

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