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在后化疗腹膜后淋巴结清扫期间为非精原细胞瘤生殖细胞肿瘤行肾下下腔静脉和腹主动脉完全血管置换。

Complete Vascular Replacement of the Infrarenal Inferior Vena Cava and Abdominal Aorta during Post-Chemotherapy Retroperitoneal Lymph Node Dissection for a Non-Seminomatous Germ Cell Tumor.

机构信息

Department of Urology, School of Health Sciences, Faculty of Medicine, University of Thessaly, University Hospital of Larissa, 41110 Larissa, Greece.

Department of Vascular Surgery, School of Health Sciences, Faculty of Medicine, University of Thessaly, University Hospital of Larissa, 41110 Larissa, Greece.

出版信息

Curr Oncol. 2023 Jun 4;30(6):5448-5455. doi: 10.3390/curroncol30060412.

DOI:10.3390/curroncol30060412
PMID:37366895
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10296946/
Abstract

Testicular germ cell tumors (TGCTs) are the leading cause of cancer-related death in males between the ages of 20 and 40. In the advanced stages, the combination of cisplatin-based chemotherapy and surgical excision of the remaining tumor can cure many of these patients. Vascular procedures may be required during retroperitoneal lymph node dissection (RPLND) in order to achieve the complete excision of all residual retroperitoneal masses. Careful assessment of pre-operative imaging and the identification of patients who could benefit from additional procedures are important for minimizing peri- and postoperative complications. We report on a case of a 27-year-old patient with non-seminomatous TGCT, who successfully underwent post-chemotherapy RPLND with additional infrarenal inferior vena cava (IVC) and complete abdominal aorta replacement using synthetic grafts.

摘要

睾丸生殖细胞肿瘤 (TGCTs) 是 20 至 40 岁男性癌症相关死亡的主要原因。在晚期,顺铂为基础的化疗与剩余肿瘤的手术切除相结合,可以治愈许多此类患者。在腹膜后淋巴结清扫术 (RPLND) 过程中,可能需要血管手术,以实现所有残余腹膜后肿块的完全切除。仔细评估术前影像学检查,并确定哪些患者可能受益于额外的手术,对于减少围手术期并发症非常重要。我们报告了一例 27 岁非精原细胞瘤 TGCT 患者的病例,该患者成功接受了化疗后 RPLND 手术,术中使用合成移植物额外进行了肾下下腔静脉 (IVC) 和整个腹主动脉置换。

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本文引用的文献

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Preoperative clinical and radiographic predictors of major vascular surgery in patients with testicular cancer undergoing post-chemotherapy residual tumor resection (PC-RPLND).在接受化疗后残余肿瘤切除(PC-RPLND)的睾丸癌患者中,主要血管手术的术前临床和影像学预测因素。
World J Urol. 2022 Feb;40(2):349-354. doi: 10.1007/s00345-021-03870-8. Epub 2021 Nov 3.
2
Outcomes of Postchemotherapy Retroperitoneal Lymph Node Dissection from a High-volume UK Centre Compared with a National Data Set.英国一家大型中心与全国数据集相比,化疗后腹膜后淋巴结清扫术的结果
Eur Urol Open Sci. 2021 Sep 30;33:83-88. doi: 10.1016/j.euros.2021.09.005. eCollection 2021 Nov.
3
Robotic retroperitoneal lymph node dissection for primary and post-chemotherapy testis cancer.
机器人辅助腹膜后淋巴结清扫术治疗原发性及化疗后睾丸癌
J Robot Surg. 2022 Apr;16(2):369-375. doi: 10.1007/s11701-021-01252-1. Epub 2021 May 12.
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Testicular Cancer, Version 2.2020, NCCN Clinical Practice Guidelines in Oncology.睾丸癌,第 2.2020 版,NCCN 肿瘤学临床实践指南。
J Natl Compr Canc Netw. 2019 Dec;17(12):1529-1554. doi: 10.6004/jnccn.2019.0058.
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Recent global trends in testicular cancer incidence and mortality.睾丸癌发病率和死亡率的近期全球趋势。
Medicine (Baltimore). 2018 Sep;97(37):e12390. doi: 10.1097/MD.0000000000012390.
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Clinical and Radiographic Predictors of Great Vessel Resection or Reconstruction During Retroperitoneal Lymph Node Dissection for Testicular Cancer.睾丸癌腹膜后淋巴结清扫术中大血管切除或重建的临床及影像学预测因素
Urology. 2019 Jan;123:186-190. doi: 10.1016/j.urology.2018.08.028. Epub 2018 Sep 1.
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ESMO Consensus Conference on testicular germ cell cancer: diagnosis, treatment and follow-up.ESMO 睾丸生殖细胞癌共识会议:诊断、治疗和随访。
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Surgical management of complex residual masses following systemic chemotherapy for metastatic testicular germ cell tumours.全身化疗治疗转移性睾丸生殖细胞肿瘤后复杂残留肿块的手术治疗。
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