Alturki Sumia, Al Amad Mohammed, Mahyoub Esam, Al Hanash Noora, Alhammadi Abdulbary
Yemen Field Epidemiology Training Program, Ministry of Public Health and Population, Sana'a City, Yemen.
Yemen National Tuberculosis Center Program, Ministry of Public Health and Population, Sana'a City, Yemen.
Epidemiologia (Basel). 2023 Jun 13;4(2):202-211. doi: 10.3390/epidemiologia4020021.
Diabetes mellitus (DM) is one of tuberculosis' (TB) ending barriers. TB patients with DM are at a higher risk than non-diabetes patients to develop complication, relapse and die. In Yemen, information on TB-DM comorbidity is lacking. This study aimed to determine the prevalence and associated factors of diabetes among TB patients at the National Tuberculosis Center (NTC) in Sana'a. A facility-based cross-sectional study was conducted. All TB patients aged >15 years who attended the NTC from July to November 2021 were screened for DM. Socio-demographic and behavioral information were collected through face-to-face interviews using questionnaires. A total of 331 TB patients were enrolled, 53% were males, 58% aged <40 years, and 74% were newly diagnosed with TB. Overall, DM prevalence was 18%. Higher rates of DM were found among TB patients that were male (OR = 3.0; 95% CI; 1.4-6.7), ≥50 years of age (OR = 10.8; 95% CI; 4.3-27.3), and those with a family history of diabetes (OR = 3.4; 95% CI; 1.6-6.9). Almost one fifth of TB patients had DM. The early detection of DM through immediate screening after a TB diagnosis and periodically during the course of treatment is crucial for TB patients' optimal care. Dual diagnostics for reducing the dual burden of TB-DM comorbidity is recommended.
糖尿病(DM)是结核病(TB)治疗的障碍之一。患有糖尿病的结核病患者比非糖尿病患者发生并发症、复发和死亡的风险更高。在也门,缺乏关于结核病合并糖尿病的信息。本研究旨在确定萨那市国家结核病中心(NTC)结核病患者中糖尿病的患病率及相关因素。开展了一项基于机构的横断面研究。对2021年7月至11月在NTC就诊的所有年龄大于15岁的结核病患者进行糖尿病筛查。通过问卷调查采用面对面访谈收集社会人口学和行为信息。共纳入331例结核病患者,其中53%为男性,58%年龄小于40岁,74%为新诊断的结核病患者。总体而言,糖尿病患病率为18%。在男性结核病患者(比值比=3.0;95%置信区间;1.4-6.7)、年龄≥50岁的患者(比值比=10.8;95%置信区间;4.3-27.3)以及有糖尿病家族史的患者(比值比=3.4;95%置信区间;1.6-6.9)中发现糖尿病发病率较高。几乎五分之一的结核病患者患有糖尿病。在结核病诊断后立即进行筛查并在治疗过程中定期进行筛查,以便早期发现糖尿病,这对结核病患者的最佳治疗至关重要。建议采用双重诊断以减轻结核病合并糖尿病的双重负担。