Ahmed H, Shakshak M, Trompeter A
St George's, University of London, UK.
Ann R Coll Surg Engl. 2023 Jun 27. doi: 10.1308/rcsann.2023.0022.
The need for bone tissue to heal effectively is paramount given its role in the mechanical support of tissues. Bone has a very good natural healing potential in comparison with most other tissue types, largely regenerating to its pre-injury state in the vast majority of cases. Certain factors such as high energy trauma, tumour resection, revision surgery, developmental deformities and infection can lead to the formation of bone defects, where the intrinsic healing potential of bone is diminished owing to bone loss. Various approaches to resolving bone defects exist in current practice, each with their respective benefits and drawbacks. These include bone grafting, free tissue transfer, Ilizarov bone transport and the Masquelet induced membrane technique. This review focuses on evaluating the Masquelet technique, discussing its method and underlying mechanisms, the effectiveness of certain modifications, and its potential future directions.
鉴于骨组织在组织机械支撑方面的作用，其有效愈合的需求至关重要。与大多数其他组织类型相比，骨具有非常良好的自然愈合潜力，在绝大多数情况下能基本再生至损伤前状态。某些因素，如高能量创伤、肿瘤切除、翻修手术、发育畸形和感染，可导致骨缺损的形成，由于骨质流失，骨的内在愈合潜力会减弱。目前临床上存在多种解决骨缺损的方法，每种方法都有其各自的优缺点。这些方法包括骨移植、游离组织移植、Ilizarov骨搬运和Masquelet诱导膜技术。本综述重点评估Masquelet技术，讨论其方法和潜在机制、某些改良的有效性及其未来潜在的发展方向。
