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草甘膦对海洋多毛类蠕虫雌性生殖产出的影响

Effects of Glyphosate on Female Reproductive Output in the Marine Polychaete Worm .

作者信息

Schleicherová Dáša, Prearo Marino, Di Nunno Crystal, Santovito Alfredo

机构信息

Department of Life Sciences and Systems Biology, University of Turin, Via Accademia Albertina 13, 10124 Torino, Italy.

IZS PLV, Istituto Zooprofilattico Sperimentale del Piemonte, Via Bologna 148, 10154 Torino, Italy.

出版信息

Toxics. 2023 Jun 2;11(6):501. doi: 10.3390/toxics11060501.

Abstract

Glyphosate is a broad-spectrum herbicide widely employed in agriculture. Exposure to this genotoxic and endocrine-disrupting compound has adverse effects on terrestrial and aquatic organisms and on humans as well. Here, we explored the effects of glyphosate on female reproductive output and somatic growth rate in the marine polychaete worm, Adult focal individuals were exposed to different concentrations of pure glyphosate (0.0, 0.125 0.250, 0.500, 1.000 µg/mL) administered once a week for 3 weeks. Toxic effects and mortalities were observed at the three higher concentrations, whereas only a decrease in growth rate was noted after exposure to 0.125 µg/mL, which did not affect female allocation. An area of focus in future studies should be the effects of contaminants, their metabolites, and ecologically relevant human-driven stressors in the context of global warming.

摘要

草甘膦是一种广泛应用于农业的广谱除草剂。接触这种具有基因毒性和内分泌干扰性的化合物会对陆生和水生生物以及人类产生不利影响。在此,我们探究了草甘膦对海洋多毛类蠕虫雌性生殖产出和体细胞生长速率的影响。成年受试个体每周暴露于不同浓度的纯草甘膦(0.0、0.125、0.250、0.500、1.000微克/毫升)中,持续3周。在三个较高浓度下观察到了毒性效应和死亡率,而暴露于0.125微克/毫升后仅注意到生长速率下降,这并未影响雌性分配。未来研究的一个重点领域应该是在全球变暖背景下污染物、其代谢物以及与生态相关的人为驱动应激源的影响。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9972/10304119/4e214f91198e/toxics-11-00501-g001.jpg

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